Epidural-subcutaneous implantable analgesic pump with anti-infective function

Abstract

The invention discloses an epidural-subcutaneous buried type analgesia pump with an anti-infection function. The epidural-subcutaneous buried type analgesia pump comprises a base (2). The base (2) is internally provided with a cavity. The cavity is composed of a large circular cavity body (21) and a small circular cavity body (22). The large circular cavity body (21) is located over the small circular cavity body (22). The lower end of a silica gel cover assembly (4) is connected with the large circular cavity body (21) in a seamless mode. The small circular cavity body (22) is internally provided with a barrel-shaped antibacterial coating inner container (3). A guide pipe assembly (1) is only communicated with the small circular cavity body (22). The antibacterial coating inner container (3) is manufactured by the following steps that raw materials are obtained by mixing clay powder and medical paraffin according to the mass ratio of 100:5-20; the raw materials are made into the required barrel shape through a die, pressureless sintering at 1600 DEG C to 1700 DEG C is conducted for 2 to 4 hours, and the inner container is obtained; the surface of the inner container is loaded with an antibacterial coating.

Description

technical field [0001] The invention relates to a subcutaneous buried analgesic pump, in particular to an epidural-subcutaneous buried analgesic pump with anti-infection function. Background technique [0002] The epidural-subcutaneous implanted analgesic pump is mainly used in the pain treatment of cancer patients. It is an ideal and innovative analgesic treatment plan, and has advantages that other analgesic methods cannot match. However, the indwelling catheter in the epidural space is one of the risk factors for epidural infection. Some studies have pointed out that if the indwelling time of the epidural catheter is within two or three days, the incidence of epidural infection is very low. However, the incidence of catheter infection after prolonged indwelling will be greatly increased, even reaching 4.3%. In addition, the epidural injection system is also one of the risk factors for epidural abscess, especially when repeated injections of drugs need to be indwelled for...

AI Technical Summary

Problems solved by technology

However, chitosan also has many shortcomings, such as insufficient persistence of action; anti-bacteria needs to be carried out under acidic conditions, which is easy to cause damage to the substrate, etc.

[0006] At present, most of the existing nano-silver antibacterial coatings use the "top-down" method to mechanically grind and disperse the silver and then add it to the coating. This method consumes a lot of energy and has poor effects, and the nano-silver particles in the prepared antibacterial coating have the following disadvantages : ① poor dispersion (easy to agglomerate); ② large particle size and large particle size distribution (poor antibacterial effect, the addition of nano silver needs to be increased under the same antibacterial ability, high cost and waste, etc.); The pH of the particle suspension and the coating itself is not the same (the dispersant in the suspension fails), which will lead to the aggregation of nanoparticles and make the coating have no antibacterial properties

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