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Composition having blood sugar-lowering and lipid-lowering effects

A technology for lowering blood sugar and lipids and compositions, which is applied in the field of compositions, can solve problems such as focus, toxic and side effects, and uncertainties, and achieve good effects of lowering blood sugar and lipids, less toxic and side effects, and a high safety range

Inactive Publication Date: 2015-07-01
HANGZHOU HUANTE BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A large number of natural plant health products or medicines with better curative effects have been developed, but these health care products or medicines only focus on a single disease, and many of them have uncertain and / or toxic and side effects of lowering blood sugar and lipids, and high blood fat and high blood pressure. Blood sugar often appears in a patient at the same time, so there is a broad market demand for developing a drug or health care product that is a natural plant composition that is highly effective, safe and has the effect of lowering blood sugar and lipids

Method used

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  • Composition having blood sugar-lowering and lipid-lowering effects
  • Composition having blood sugar-lowering and lipid-lowering effects
  • Composition having blood sugar-lowering and lipid-lowering effects

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The traditional Chinese medicine composition with hypoglycemic and lipid-lowering effects is prepared by grinding 1000 g of eucommia leaves, 100 g of eucommia male flowers, and 100 g of cinnamon into powder, passing through a 100-mesh sieve, and mixing the powders evenly.

[0041]

Embodiment 2

[0043] The traditional Chinese medicine composition with hypoglycemic and lipid-lowering effects is obtained by extracting eucommia ulmoides leaves, eucommia male flowers, and cinnamon separately and mixing them. The extraction steps are as follows:

[0044] Take 1000 g of eucommia leaves according to the formula, add 70% ethanol aqueous solution to extract twice, each time for 2 hours, add 70% ethanol aqueous solution for the first extraction, the amount of solvent added is 12 times the weight of the medicinal material, and the solvent added for the second time The amount is 10 times the weight of the medicinal material, the extracts are combined, filtered, concentrated under reduced pressure, and dried to obtain 328 g of dry matter.

[0045] Take 100 g of eucommia male flowers according to the formula, add 60% ethanol aqueous solution to extract twice, each time for 2 hours, add 60% ethanol aqueous solution for the first extraction, the amount of solvent added is 15 times the...

Embodiment 3

[0049] Take 1000 g of Eucommia leaves, 100 g of Eucommia male flowers, and 100 g of cinnamon according to the formula, add water to extract twice, each time for 2 hours, the amount of water added for the first extraction is 12 times the weight of the medicinal materials, and the amount of water added for the second time is 10 times the weight of the medicinal materials, combined the extracts, filtered, concentrated under reduced pressure, and dried to obtain 387 g of dry matter.

[0050] Crush the above-mentioned dry matter, pass through a 100-mesh sieve, add microcrystalline cellulose, crospovidone, and magnesium stearate, mix evenly, and fill capsules to obtain the product. The ratio of dry matter to auxiliary materials is: 2:1~5 :1.

[0051]

[0052] In order to confirm the excellent curative effect of the present invention in reducing blood sugar and lipids, the following further introduces the results obtained in various pharmacological studies of the composition f...

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Abstract

The invention relates to a composition having a blood sugar-lowering and lipid-lowering synergistic effect, and is used for preventing and treating hyperglycemia and hyperlipidemia. The blood sugar-lowering and lipid-lowering composition is composed of eucommia ulmoides leaves, eucommia ulmoides male flowers and cinnamon, and the adding amounts of the components comprise 50-150 parts of the eucommia ulmoides leaves, 5-25 parts of the eucommia ulmoides male flowers, and 5-50 parts of the cinnamon. Pharmacological experiments prove that the composition has the blood sugar-lowering effect, and can inhibit gluconeogenesis and promote glycometabolism simultaneously; at the same time, the composition has relatively good lipid-lowering effect. The blood sugar-lowering and lipid-lowering composition has the blood sugar-lowering and lipid-lowering effects superior to single components, and has the cooperative synergistic effect. The composition has the advantages of definite blood sugar-lowering and lipid-lowering effects, novel formulation, blood sugar-lowering and lipid-lowering synergistic effects, reliable curative effect and no obvious toxic or side effect, is a traditional Chinese medicine, also can lower blood sugar and lipid, provides a good formula, and can be used in preparation of drugs or health-care products for treating and preventing hyperglycemia and hyperlipidemia.

Description

technical field [0001] The invention relates to a composition, in particular to a composition composed of leaves of eucommia ulmoides, male flowers of eucommia ulmoides and cinnamon, which has synergistic effects of lowering blood sugar and lipids. Background technique [0002] Diabetes is a series of clinical syndromes caused by absolute or relative insufficiency of insulin in the body, and is one of the most common chronic diseases [1] . Different types of diabetes can cause the beta cells in the pancreas to fail to produce enough insulin to lower blood sugar levels, resulting in hyperglycemia. With the improvement of people's living standards, the aging population and the increase in the incidence of obesity, the incidence of diabetes is increasing year by year. According to the International Diabetes Federation (IDF), more than 285 million people worldwide live with diabetes, a number that will soar to 435 million by 2030. Diabetes affects 7% of the world's total adul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P3/10A61P3/06
Inventor 李春启朱桃桃宋如顺
Owner HANGZHOU HUANTE BIOLOGICAL TECH CO LTD
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