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Traditional Chinese medicine granular preparation for treating osteoporosis

A technology for osteoporosis and traditional Chinese medicine granules, which can be used in bone diseases, drug combinations, pharmaceutical formulations, etc., and can solve problems such as lack of therapeutic drugs

Inactive Publication Date: 2015-08-26
NANJING HUAKUANG INFORMATION CONSULTING CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The market lacks effective therapeutic drugs

Method used

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  • Traditional Chinese medicine granular preparation for treating osteoporosis

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Experimental program
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Effect test

Embodiment 1

[0016] Embodiment 1: Get 18g of broad tendon rattan, 20g of hangzi shoots in southern Yunnan, 15g of birch flat bamboo, 10g of rice tree, and 20g of small blue flower, and the above-mentioned Chinese medicines are added to CO in a supercritical extractor, and ethanol is used as an entraining agent to entrain The volume percentage of solvent in the total extraction solvent is 5%, the extraction pressure is 20MPa, the temperature is 40°C, the CO2 flow rate is 2m1 / g crude drug·min, and the extraction time is 160min to obtain a supercritical extract, add 70% ethanol, and put it into a microwave extraction device for extraction. Microwave extraction, extraction power 500W, extraction 2 times, 6 minutes each time, the amount of 70% ethanol added each time is 2 times the weight of medicinal materials, to obtain the extract, concentrated, added to D101 macroporous adsorption resin column, 50% For ethanol elution, collect 5 times the column volume eluate, recover ethanol under reduced p...

Embodiment 2

[0017] Embodiment 2: Get 18g of broad tendon rattan, 20g of Diannan hangzi shoots, 15g of birch flat bamboo, 10g of rice tree, and 20g of small blue flower, and the above-mentioned Chinese medicines are added to CO in a supercritical extractor, and ethanol is used as an entraining agent to entrain The volume percentage of solvent in the total extraction solvent is 4%, the extraction pressure is 30MPa, the temperature is 30°C, the CO2 flow rate is 3m1 / g crude drug·min, and the extraction time is 150min to obtain a supercritical extract, add 70% ethanol, and put it into a microwave extraction device for extraction. Microwave extraction, extraction power -600W, extraction 2 times, 4 minutes each time, the amount of 70% ethanol added each time is 2 times the weight of the medicinal material, to obtain the extract, concentrated, added to the D101 macroporous adsorption resin column, 50 % ethanol for elution, collect 5 times the column volume eluate, recover ethanol under reduced pre...

Embodiment 3

[0018] Embodiment 3: Get 18g of broad tendon rattan, 20g of hangzi shoots in southern Yunnan, 15g of flat bamboo, 10g of rice tree, and 20g of small blue flower, and the above-mentioned Chinese medicines are added to CO in a supercritical extractor, and ethanol is used as an entraining agent to entrain The volume percentage of solvent in the total extraction solvent is 6%, the extraction pressure is 15MPa, the temperature is 50°C, the CO2 flow rate is 1m1 / g crude drug·min, and the extraction time is 150min to obtain a supercritical extract, add 70% ethanol, and put it into a microwave extraction device for extraction. Microwave extraction, extraction power 600W, extraction 2 times, 4 minutes each time, the amount of 70% ethanol added each time is 2 times the weight of medicinal materials, to obtain the extract, concentrated, added to D101 macroporous adsorption resin column, 50% For ethanol elution, collect 5 times the column volume eluate, recover ethanol under reduced pressur...

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Abstract

The invention provides a traditional Chinese medicine granular preparation for treating osteoporosis and belongs to the field of traditional Chinese medicine preparations. The traditional Chinese medicine granular preparation is prepared by extracting traditional Chinese medicines as follows: 18 parts of caulis tinosporae sinensis, 20 parts of campylotropis rockii schindl, 15 parts of all-grass of irisleaf oberonia, 10 parts of flueggea virosa and 20 parts of philippine violet herb. The traditional Chinese medicine granular preparation can increase the bone mineral density and treat osteoporosis.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine extraction, in particular to a traditional Chinese medicine granule for treating osteoporosis, a preparation method and application thereof. Background technique [0002] Osteoporosis, or osteoporosis, is a group of bone diseases caused by a variety of reasons. Bone tissue has normal calcification, and the ratio of calcium salt to matrix is ​​normal. It is a metabolic bone lesion characterized by a decrease in the amount of bone tissue per unit volume. . In most cases of osteoporosis, the loss of bone tissue is mainly due to increased bone resorption. Characterized by bone pain and susceptibility to fractures. The market lacks effective therapeutic drugs. Contents of the invention [0003] Purpose of the invention: In order to solve the above problems, the purpose of the present invention is to provide a kind of traditional Chinese medicine granule for treating osteoporos...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/16A61P19/08
Inventor 李洋
Owner NANJING HUAKUANG INFORMATION CONSULTING CENT
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