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Anti-helicobacter-pylori composition and preparation method thereof

A Helicobacter pylori and composition technology, applied in the field of compound probiotics and compound traditional Chinese medicine enzymes, can solve the problems of high toxicity and side effects, increase drug resistance of bacterial strains, etc., reduce toxicity and side effects, and change the acid-base environment of the stomach , a significant inhibitory effect

Inactive Publication Date: 2015-09-02
上海利康精准医疗技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The current method for treating Hp is mainly based on the "triple" or "quadruple" therapy of antibiotics. The use of antibiotics not only increases the drug resistance of bacterial strains, but also has large toxic and side effects. Substitutes with bacillus effect and less side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] A. Preparation of compound Chinese herbal enzyme powder

[0045] The components and parts by weight of the Chinese medicine combination in the present embodiment are as follows:

[0046] 8 parts of rhodiola, 8 parts of wolfberry, 6 parts of Cordyceps fungus, 6 parts of astragalus, 8 parts of coix seed, 16 parts of hawthorn, 16 parts of sealwort, 16 parts of Chinese yam, 15 parts of forsythia, 20 parts of raw licorice, 5 parts of sophora, Coptis chinensis 5 parts, 5 parts of Banlangen, 20 parts of Hericium erinaceus.

[0047] (1) Clean the decoction pieces of traditional Chinese medicine in the above ratio, disinfect them with ozone, chop them into small pieces with a side length not greater than 1cm, and put them into a sterile fermenter;

[0048] (2) After adding yeast, ferment at 28°C for 45 days, then ferment at 31°C for 45 days, then add lactic acid bacteria and natto bacteria and ferment at 35°C for 45 days, then control the pH value to 2-3, at 40 Continue to fer...

Embodiment 2

[0056] A. Preparation of compound Chinese herbal enzyme powder

[0057] The components and parts by weight of the Chinese medicine combination in the present embodiment are as follows:

[0058] 6 parts of rhodiola, 6 parts of wolfberry, 5 parts of cordyceps, 6 parts of astragalus, 5 parts of barley, 5 parts of hawthorn, 5 parts of sealwort, 6 parts of yam, 5 parts of forsythia, 10 parts of raw licorice, 5 parts of sophora, Coptis chinensis 2 parts, 4 parts of Banlangen, 5 parts of Hericium erinaceus.

[0059] (1) Clean the decoction pieces of traditional Chinese medicine in the above ratio, disinfect them with ozone, chop them into small pieces with a side length not greater than 1cm, and put them into a sterile fermenter;

[0060] (2) After adding yeast and Monascus, ferment at 28°C for 45 days, then ferment at 31°C for 45 days, then add lactic acid bacteria and ferment at 35°C for 45 days, then control the pH value to 2-3, at 40 Continue to ferment at ℃ for 45 days, stir o...

Embodiment 3

[0068] A. Preparation of compound Chinese herbal enzyme powder

[0069] The components and parts by weight of the Chinese medicine combination in the present embodiment are as follows:

[0070] 3 parts of rhodiola, 8 parts of wolfberry, 7 parts of Cordyceps fungus, 6 parts of astragalus, 1 part of barley, 2 parts of hawthorn, 2 parts of sealwort, 10 parts of Chinese yam, 20 parts of forsythia, 12 parts of raw licorice, 1 part of sophora, Coptis chinensis 1 portion, 1 portion of Banlangen, 25 Hericium erinaceus.

[0071] (1) Clean the decoction pieces of traditional Chinese medicine in the above ratio, disinfect them with ozone, chop them into small pieces with a side length not greater than 1cm, and put them into a sterile fermenter;

[0072] (2) Ferment at 28°C for 45 days after adding yeast, acetic acid bacteria and Monascus, then ferment at 31°C for 45 days, then add lactic acid bacteria and ferment at 35°C for 45 days, then control the pH value to 2-3 , continue to ferme...

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Abstract

The invention discloses an anti-helicobacter-pylori composition and a preparation method thereof. The composition is a powdery preparation, and comprises 10 to 90 parts of compound probiotic bacterium powder, and 10 to 90 parts of compound traditional Chinese medicinal ferment powder. Probiotics and lactoferrin can be further added into the composition, and the anti-helicobacter-pylori composition can be used as a supplement and an additive of a food or a pharmaceutical ingredient. According to the composition which is provided by the invention, the function that a traditional Chinese medicine restrains Hp (helicobacter pylori) is utilized; meanwhile, the toxic and side effects of the traditional Chinese medicine are decreased; added compound probiotic bacteria not only can effectively restrain the Hp per se, but also can further promote the further absorption of traditional Chinese medicinal ferments at the same time. Shown by study, the composition provided by the invention can be used for curing an Hp infection, and therefore, has a favorable application prospect in the preparing of an anti-Hp medicine.

Description

technical field [0001] The invention relates to an anti-helicobacter pylori composition and a preparation method thereof, in particular to a composition of an anti-helicobacter pylori compound probiotic and a compound traditional Chinese medicine enzyme. Background technique [0002] Helicobacter pylori (Hp) is a Gram-negative microaerophilic bacillus. Since Warren and Marshall, winners of the Nobel Prize in Physiology and Medicine in 2005, isolated Hp from gastroscopic biopsy specimens of patients with chronic gastritis in 1979, they have received great attention from many scholars in the medical field at home and abroad. [0003] Hp is a unipolar, multi-flagellated, blunt-rounded, spirally curved bacterium with 1 to 2 tiny bends, 2 to 4 μm in length, 0.5 to 1.0 μm in width, and only one circular chromosome. [0004] The Hp infection rate varies among different populations, and the diversity of clinical outcomes after Hp infection suggests the complexity of its pathogenic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K36/8969A61K36/8945A61K36/734A61K36/718A61K36/634A61K36/489A61K36/484A61K36/481A61K36/41A61K36/195A61K36/315A23L1/29A61P31/04A61K35/741A61K35/744
Inventor 毛丹丹卞雪莲邹创傅咏南王校
Owner 上海利康精准医疗技术有限公司
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