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Application of ulinastatin for preparing cervical cancer treatment medicine and pharmaceutical composition

A technology of ulinastatin and its composition, which is applied in the field of pharmaceutical composition for the treatment of cervical cancer, can solve the problems of aggravating the pain of patients and the high incidence of peripheral neuropathy, and achieve improved compliance, synergistic anti-cancer effect, and significant The effect of action

Active Publication Date: 2015-09-16
GUANGDONG TECHPOOL BIO-PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of paclitaxel to treat cancer has a high incidence of adverse reactions such as allergic reactions, peripheral neuropathy, and alopecia, which aggravate the suffering of patients

Method used

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  • Application of ulinastatin for preparing cervical cancer treatment medicine and pharmaceutical composition
  • Application of ulinastatin for preparing cervical cancer treatment medicine and pharmaceutical composition
  • Application of ulinastatin for preparing cervical cancer treatment medicine and pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Ulinastatin 57.14 mg artesunate 22.86mg

[0019] Preparation process: take the prescribed amount of ulinastatin and artesunate, dissolve in 500ml 0.9% normal saline injection, filter, pot, and sterilize at 100°C for 30 minutes.

Embodiment 2

[0021] Ulinastatin 57.14 mg artesunate 45.71mg

[0022] Preparation process: take the prescribed amount of ulinastatin and artesunate, dissolve in 500ml 0.9% normal saline injection, filter, pot, and sterilize at 100°C for 30 minutes.

Embodiment 3

[0024] Ulinastatin 57.14 mg artesunate 2.857mg

[0025] Preparation process: take the prescribed amount of ulinastatin and artesunate, dissolve in 500ml 0.9% normal saline injection, filter, pot, and sterilize at 100°C for 30 minutes.

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Abstract

The invention belongs to the field of medical technology and discloses a new application of ulinastatin for preparing cervical cancer treatment medicine and a pharmaceutical composition for treating cervical cancer. The pharmaceutical composition includes ulinastatin and artesunate, and the pharmaceutical composition can include paclitaxel medicine specifically paclitaxel. The pharmaceutical composition has a synergistic effect for inhibiting cervical cancer and has advantages of low toxic and side effects, obvious cancer inhibition effect and the like.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the use of ulinastatin in the preparation of medicines for treating cervical cancer, and a pharmaceutical composition containing ulinastatin for treating cervical cancer. Background technique [0002] Cervical cancer refers to malignant tumors that occur at the junction of squamous epithelial cells of the cervicovaginal or transition zone and columnar epithelial cells of the endocervical endometrium. Cervical cancer is the most common malignant tumor of the cervix in female reproductive system tumors. The clinical manifestations of menstruation or excessive leucorrhea, irregular vaginal bleeding, waist and abdomen pain, anemia, emaciation and other systemic debilitating symptoms. In recent years, the incidence of cervical cancer has continued to rise, and the incidence of cervical cancer is gradually becoming younger. The long-term clinical point of view is that the...

Claims

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Application Information

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IPC IPC(8): A61K38/17A61P35/00A61P15/00A61K31/357A61K31/337
Inventor 王旭郑少亮许文勤肖益热
Owner GUANGDONG TECHPOOL BIO-PHARMA CO LTD
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