Spray nozzle with double flow channels

Abstract

The invention provides a spray nozzle with double flow channels. The spray nozzle comprises a spray nozzle unit with the inner flow channel, a spray nozzle unit with the outer flow channel, a connector and a spray nozzle body. The spray nozzle unit with the inner flow channel and the spray nozzle unit with the outer flow channel are connected to the spray nozzle body by the connector, and a spinneret structure is formed in the spray nozzle body in such a manner that an inner-layer material squeezed out of the spray nozzle unit with the inner flow channel is positioned in the center of the spinneret structure and an outer-layer material squeezed out of the spray nozzle unit with the outer flow channel wraps the periphery of the spinneret structure. The spray nozzle with the double flow channels has the advantages that the two different materials are respectively arranged in the inner flow channel and the outer flow channel by the aid of inner and outer double-flow-channel technologies, accordingly, the spinneret structure with the corresponding material in the center and the other material uniformly arranged on the periphery can be formed by means of squeezing, the central material can be effectively protected, and cell substances in the center of the spray nozzle can be protected when the spray nozzle is applied to 3D (three-dimensional) biological printing; nutrients can be provided, so that the survival rate of printed biological cells can be increased.

Description

technical field [0001] The invention belongs to the field of biomedical engineering, in particular to a double-channel nozzle. Background technique [0002] Based on the principles of existing 3D printing technology, 3D bioprinters use layers of biological building blocks to manufacture real living tissues. Mainly use pre-extracted living bodies, combine and arrange, print out the required cells, the error can be controlled within 20 microns, and the obtained organs can significantly reduce rejection, which is an important technical breakthrough in organ transplantation in the biomedical field. [0003] When using a 3D bioprinter to print biomaterials and cell complexes to build biological tissues and organs, the traditional method is to uniformly mix cells and biomaterials and spray them out through a single nozzle. The pressure causes the cells to be damaged, and the viability of the cells decreases. After the cells and biomaterials are printed, due to the lack of nutrien...

AI Technical Summary

Problems solved by technology

[0003] When using a 3D bioprinter to print biomaterials and cell complexes to build biological tissues and organs, the traditional method is to uniformly mix cells and biomaterials and spray them out through a single nozzle. The pressure causes the cells to be damaged, and the viability of the cells decreases. After the cells and biomaterials are printed, due to the lack of nutrients and space around them, the metabolism, expansion and differentiation of the cells are affected, which affects the subsequent culture of the constructed tissues and organs.

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