An analog front-end detection circuit and detection method of an immune test strip reader

Abstract

The invention aims to provide an analog front end detection circuit and detection method for an immune strip reading instrument. The detection circuit includes a strip background amplitude collection unit and a strip background amplitude correction unit. The detection method includes the following steps: optical signals are collected and output to the strip background amplitude correction unit by the strip background amplitude collection unit after an optical mechanism acquires the optical signals of a strip background zone; the obtained signals are processed by the strip background amplitude correction unit. Through the adoption of the technical scheme provided by the invention, background amplitude is well stabilized, so that immune strip quantitative determination and qualitative interpretation are quicker and more accurate, besides, the background amplitude can be effectively controlled, and further, the detection range and resolving power of the immune strip reading instrument are improved; the technical scheme provided by the invention can be widely applied to fields such as medical POCT and food safety testing, and can effectively solve the defect that the instrument is lowered in performances due to deviation of the background amplitude of the immune strip.

Description

technical field [0001] The invention relates to immune chromatography technology, in particular to an analog front-end detection circuit of an immune test strip reader and a detection method thereof. Background technique [0002] Immunochromatography is a rapid detection technology that has emerged rapidly in recent years. Colloidal gold, latex particles, magnetic beads, fluorescein, etc. are often used as tracer markers to detect antigen-antibody reactions. This technology has the advantages of simple and fast operation, high sensitivity, strong specificity, good stability, accurate results, and easy judgment. [0003] The patent (application number: 201010255284.0) proposes a fluorescence detector that controls the aperture of the light source through a beam limiting device to adjust the optical properties. The upper limit of the concentration of the measurable sample is increased, thereby improving the dynamic range of the measurement. (Application No.: 201210200826.3) ...

AI Technical Summary

Problems solved by technology

[0005] In view of this, the present invention proposes a method for designing an analog front-end detection circuit of an immune test strip reader, which is used to solve the problem of fluctuations in the background detection amplitude of the immune test strip

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