A Piston Ventricular Simulator for Simulating the Circulatory System Outside the Body

A circulatory system and in vitro simulation technology, which is applied in the field of simulators, can solve the problems that the passive filling of the ventricle cannot be accurately simulated, the physiological response of the human body cannot be simulated realistically, and the passive filling of the ventricle is not realized. Simple to drive

Active Publication Date: 2018-11-30
MAGASSIST CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Huang Huan (indirect measurement of aortic flow in simulated circulatory system [J]. Journal of Shanghai Jiao Tong University, 2012, 07 (7): 1138-1141) designed a simulated circulatory system, such as figure 1 As shown, the left ventricle actively controls the contraction or relaxation of the ventricle through the pneumatic system, and does not realize the physiological passive filling of the ventricle, that is, the passive relaxation of the ventricle. The passive filling of the simulated ventricle cannot be accurately simulated. Although the contraction function of the ventricle to pump blood is satisfied, This simulated circulatory system cannot truly simulate the physiological response of the human body after cardiovascular intervention
[0004] Ventricular simulators developed abroad that can realize the Frank-Starling mechanism use gas-driven silicone ventricles, the drive system is large in size, and it is difficult to achieve precise and rapid movement control

Method used

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  • A Piston Ventricular Simulator for Simulating the Circulatory System Outside the Body
  • A Piston Ventricular Simulator for Simulating the Circulatory System Outside the Body
  • A Piston Ventricular Simulator for Simulating the Circulatory System Outside the Body

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Effect test

Embodiment 1

[0027] Such as figure 2 As shown, a piston-type ventricular simulator for simulating the circulatory system in vitro includes a ventricle 2, a piston 4, and a driving mechanism. The lower end of the ventricle 2 is provided with a liquid inlet 6 and a liquid outlet 8. Clearance fit, the piston 4 is connected with the drive mechanism, and the drive mechanism drives the piston 4 to move downward in a straight line to realize the active contraction of the ventricle 2. When the driving force of the drive mechanism disappears, due to the clearance fit between the piston 4 and the inner wall of the ventricle 2, the simulated circulatory system The internal force, that is, simulates the circulation of liquid in the circulatory system. The pressure difference formed between the liquid inlet 6 and the liquid outlet 8 drives the piston 4 to move upward in a straight line to realize the passive relaxation of the ventricle 2, that is, to realize the passive filling of the ventricle 2.

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Embodiment 2

[0052] Such as Figure 10 As shown, the difference between the second embodiment and the first embodiment is that the driving mechanism is a ball screw motor 42 , the ball screw motor 42 includes a rotating motor 44 and a ball screw 46 , and the ball screw 46 is connected to the piston 4 .

[0053] The passive filling simulation process of the ventricle 2 is as follows: first, the rotation motor 44 is given a given number of executions per minute according to the different heart rates of the people. The ratio of the systolic phase to the diastolic phase adjusts the time ratio between the downward linear motion of the piston 4 and the upward linear motion. The time of the downward linear motion of the piston 4 is also the time when the rotary motor 44 is powered on. At the beginning, the rotary motor 44 is powered on, the ball screw 46 pushes the piston 4 to move downward in a straight line, the piston 4 advances, the ventricle 2 contracts, then the rotary motor 44 is powered o...

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Abstract

The invention relates to a piston type ventricular simulator for an in-vitro simulated circulation system. The piston type ventricular simulator comprises a ventricle, a piston and a drive mechanism. The lower end of the ventricle is provided with a liquid inlet and a liquid outlet. The piston is in clearance fit with the inner wall of the ventricle. The piston and the drive mechanism are connected. The drive mechanism drives the piston to move linearly and downwardly. According to the technical scheme of the invention, the piston type ventricular simulator has the advantages of easy machining, simple and accurate drive mode and the like, wherein the miniaturization of the in-vitro simulated circulation system is realized. The piston type ventricular simulator is has significant advantages in the modularization aspect. By means of a balanced-force spring, the influence on the upward linear motion of the piston is eliminated, so that the passive relaxation of the ventricle is realized. The accurate simulation of the passive filling of the ventricle is also realized.

Description

technical field [0001] The invention relates to a simulator, in particular to a piston-type ventricle simulator for simulating a circulatory system outside the body. Background technique [0002] The simulated circulatory system is a set of devices that simulate human blood circulation, providing an in vitro evaluation platform for the performance and physiological compatibility of various cardiovascular artificial organs, including testing of ventricular assist devices or artificial mechanical valves. At present, the in vitro test results obtained in the simulated circulatory system, together with animal experiments, have become an important basis for cardiovascular artificial organs to obtain clinical approval. The simulated circulatory system includes a ventricular simulator that simulates the pumping function of the ventricles and components that simulate the elasticity and resistance of blood vessels. Cardiac output, ventricular pressure, arteriovenous pressure and oth...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G09B23/30
CPCG09B23/303
Inventor 徐博翎黄柊喻
Owner MAGASSIST CO LTD
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