Solution preparation for detecting and relieving or eliminating oral inflammation, combination product and application thereof

A technology of oral inflammation and combination products, applied in the field of medical examination and oral care, can solve the problems of long and cumbersome detection process

Inactive Publication Date: 2016-02-03
潘申权
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] The previously developed oral inflammation level detection method is mainly based on the detection of the number of neutrophils in the oral cavity (refer to Chinese Patent Application No. 201010588508X), and the detection process is relatively long and cumbersome

Method used

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  • Solution preparation for detecting and relieving or eliminating oral inflammation, combination product and application thereof
  • Solution preparation for detecting and relieving or eliminating oral inflammation, combination product and application thereof
  • Solution preparation for detecting and relieving or eliminating oral inflammation, combination product and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0192] Embodiment 1: Composition and preparation of product

[0193] Take an appropriate amount of sterile distilled water into a suitable container and stir it. Then, ethanol, tannin, chlorhexidine gluconate or Yujiechun, sucralose or sodium chloride, and sodium phenol red were added in the following order. During the preparation process, the solution was kept stirring until all contents were completely dissolved.

[0194] A solution formulation comprising the following composition was prepared:

[0195] Solution preparation 1 (calculated per liter of solution) uses water as a solvent and contains: 30 grams of ethanol, 10 grams of tannin, 0.2 grams of chlorhexidine gluconate, 0.3 grams of sucralose and 0.011 grams of sodium phenol red.

[0196] Solution preparation 2 (calculated per liter of solution) uses water as a solvent and contains: 100 grams of ethanol, 7 grams of tannin, 0.2 grams of chlorhexidine gluconate, 0.3 grams of sucralose and 0.011 grams of sodium phenol ...

Embodiment 2

[0201] Example 2: Detection of polymeric precipitates formed by gargling with tannin solution

[0202] In this example, the polymeric precipitate formed by gargling with solution preparation 1 in the oral cavity of subject No. 1 who received ulcer-like spot removal treatment and subject No. 2 who did not receive corresponding treatment was tested. things.

[0203] The subject No. 1 is 50 years old with occasional bad breath and oral ulcers; the subject No. 1 is 32 years old with oral ulcers and frequent halitosis.

[0204] On June 2, 2013 and March 1, 2014, subjects No. 1 and No. 2 were tested for polymeric precipitates formed by gargling with solution preparation 1. The specific detection steps are as follows:

[0205] 1. Rinse your mouth with an appropriate amount of solution containing tannin to obtain an oral cavity solution. Use 15 ml of solution formulation 1, rinse your mouth vigorously for 30 seconds, and allow the solution formulation to fully contact all parts of...

Embodiment 3

[0214] Embodiment 3: According to the detection of the polymeric precipitate formed by gargling with tannin solution in embodiment 2 Calculation of Oral Inflammation Index

[0215] In this example, the oral inflammation index is calculated according to the detection results of the polymeric precipitate formed by gargling with the tannin solution in Example 2. As described in Table 1, subject No. 1 received ulcer-like point removal treatment, and on June 2, 2013 (before the treatment), the polymeric precipitate (P t ) was: 186 μl; On March 1, 2014 (after treatment), the aggregated precipitate (P h ) is: 1 μl, that is to say, the polymeric precipitate of the subject is reduced by 186 times. This can be inversely deduced that the experimenter's individualized oral inflammation index (I i ) is: 186 μl / 1 μl=186. And this experimenter, after treatment, its individualized oral inflammation index (I i ) is: 1 μl / 1 μl=1.

[0216] After the above-mentioned subjects have undergo...

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Abstract

The invention provides a solution preparation for detecting oral inflammation or degree of cleanliness, relieving and / or eliminating oral inflammation, and / or cleaning an oral cavity, a combination product for detecting oral inflammation degree of a mammal and relieving and / or eliminating oral inflammation, and application of a tannin solution in preparation of products for detecting oral inflammation degree, relieving or eliminating oral inflammation, detecting oral cleanliness degree, and / or cleaning the oral cavity. The invention also provides application of the solution preparation and the combination product in preparation of products for detecting the oral inflammation degree, relieving or eliminating the oral inflammation, detecting the oral cleanliness degree, and / or cleaning the oral cavity.

Description

technical field [0001] The invention belongs to the fields of medical examination and oral care, in particular, the invention relates to a solution preparation, a combination product and an application thereof for rapidly detecting and alleviating or eliminating oral inflammation. Background technique [0002] People tend to brush their teeth twice a day, morning and evening, and many people clean their teeth regularly, but many people also have oral problems, such as periodontitis, dental caries, mouth ulcers and bad breath. [0003] Oral ulcers, commonly known as oral inflammation, directly affect work efficiency. When the work is tense and busy, many people will have white blisters in the mouth, which is unbearable pain. This not only affects people's work efficiency, but also disturbs people's mood. Recurrent oral ulcers plague many people, and its etiology is still unknown. [0004] Oral inflammation affects the efficacy of various oral medical measures (such as impl...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61K31/7024A61K9/08A61K49/00A61B1/00A61P1/02A61K31/085A61K31/155
Inventor潘申权
Owner潘申权