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Medicine composition having analgesic effect and preparation method thereof

A composition and drug technology, applied in the directions of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of many adverse reactions, small toxic side effects, low cure rate, etc., and achieve remarkable analgesic effect and biological High availability, no toxic side effects

Inactive Publication Date: 2016-02-03
叶宗耀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the curative effect on the treatment of such diseases at home and abroad is not significant, the toxicity and irritation are large, and the treatment methods are inconvenient
Western medicine treatment of bone injuries requires surgery, plaster, stents, anti-inflammatory injections, etc., and the medical expenses are relatively high. Voltaren emulsion, which is commonly used in western medicine, has many adverse reactions, mainly including skin itching, redness, and tingling; There are two main types of Chinese patent medicines: Chinese patent medicines for internal use, such as Zhonghua Dieda Pills, Yunnan Baiyao, Sanqi Shangyao Tablets, Sanqi Tablets, Qili Powder, etc.; Ointment, etc., have slow effect, long course of treatment, and poor long-distance curative effect. Therefore, it is an inevitable trend to invent a painkiller with high curative effect, low cost, safety, reliability and convenience.
[0005] Chinese patent application 201110206521.9 discloses a medicinal composition for reducing swelling and relieving pain. , Artemisia argyi, safflower, ephedra, Chinese prickly ash, cinnamon and dried ginger are prepared according to a certain weight ratio. The pharmaceutical composition of the invention is prepared from Chinese herbal medicine.

Method used

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  • Medicine composition having analgesic effect and preparation method thereof
  • Medicine composition having analgesic effect and preparation method thereof
  • Medicine composition having analgesic effect and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment l

[0035] The pharmaceutical composition of Example 1 of the present invention is prepared from the following raw materials in parts by weight: 20 parts of Ophiopogon japonicus, 10 parts of Shijiaocao, 25 parts of notopterygium, 12 parts of Panax notoginseng, 15 parts of myrrh, 10 parts of cassia twig, purple Su 15 parts, centella asiatica 8 parts, angelica 10 parts, bergamot 10 parts and licorice 8 parts.

[0036] Preparation:

[0037] S1: Weigh Ophiopogon japonicus, crush it into a coarse powder, place it in a supercritical carbon dioxide extraction device, add a 60% ethanol solution with a volume fraction of 40% of the weight of the coarse powder, adjust the flow rate of carbon dioxide to 15L / h, and the extraction pressure to 20MPa, The extraction temperature is 40°C, the extraction time is 2 hours, and the Ophiopogon japonicus extract is obtained by separating under reduced pressure, and the Ophiopogon japonicus residue is retained;

[0038] S2: Weigh Shijiaocao, Notopterygium...

Embodiment 2

[0042] The pharmaceutical composition of Example 2 of the present invention is prepared from the following raw materials in parts by weight:

[0043] 30 parts of Ophiopogon japonicus, 25 parts of Shijiao grass, 10 parts of notopterygium, 18 parts of notoginseng, 12 parts of myrrh, 18 parts of cassia twig, 10 parts of perilla, 15 parts of centella asiatica, 18 parts of angelica, 15 parts of bergamot and licorice 15 servings.

[0044] The preparation method is similar to Example 1.

Embodiment 3

[0046] The pharmaceutical composition of Example 3 of the present invention is prepared from the following raw materials in parts by weight:

[0047] 15 parts of Ophiopogon japonicus, 15 parts of Shijiao grass, 15 parts of notopterygium, 15 parts of notoginseng, 18 parts of myrrh, 15 parts of cassia twig, 12 parts of perilla, 12 parts of centella asiatica, 15 parts of angelica, 18 parts of bergamot and licorice 5 servings.

[0048] The preparation method is similar to Example 1.

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicines and relates to a medicine composition having the analgesic effect. The medicine composition is mainly prepared from, by weight, 15-30 parts of ophiopogon japonicus, 10-25 parts of a sessilefruit chinaure herb, 10-25 parts of notopterygium roots, 12-18 parts of a pseudo-ginseng, 12-18 parts of myrrh, 10-18 parts of cassia twigs, 10-15 parts of purple perilla, 8-15 parts of an asiatic pennywort herb, 10-18 parts of Chinese angelica, 10-18 parts of fingered citrons and 5-15 parts of licorice. The medicine composition has the effects of relieving swelling and pain, promoting blood circulation to remove blood stasis, dispelling wind, eliminating dampness and the like, has the advantages of quick effect, good effect, treatment of both symptoms and root causes and the like on the analgesic aspect and especially has the remarkable analgesic effect on the pain caused by blood stasis and stagnation and cold dampness invasion. In addition, a preparation process of the medicine composition is simple and convenient and easy to operate, and the preparation is stable in medicinal effect, good in universality and easy to popularize and apply.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition with analgesic effect. Background technique [0002] Orthopedics soft tissue injury and bone joint lesions mainly include local or general pain, swelling, tendon injury, bruising, bleeding, skin bruising and other trauma phenomena caused by falls, knife wounds, abrasions and sports injuries, as well as trauma during breathing. Visceral injury such as internal tingling. If bruises are not treated in time, microcirculation disturbances will easily occur, resulting in the formation of blood deposits in soft tissues, which will cause aseptic inflammation and tissue swelling and pain; lead to adhesion of muscles and tendons, ischemic contracture, Symptoms such as adhesions inside and outside the joints. [0003] Chinese medicine believes that bone damage, the skin and flesh bear the brunt of the brunt, damage to the muscles and bon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P29/00A61P19/04A61P19/02
Inventor 叶宗耀
Owner 叶宗耀
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