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Self-accurate fiber-optic surface plasmon resonance biochemical detection sensor with dual modulation modes

A surface plasma and biochemical detection technology, used in instruments, measuring devices, scientific instruments, etc., can solve the problems of single modulation method, poor detection accuracy, large volume, etc., and achieve simple process, stable performance, and high response sensitivity. Effect

Active Publication Date: 2019-04-05
DALIAN UNIV OF TECH
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  • Abstract
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Problems solved by technology

[0002] At present, the dual-channel biochemical sensors using the surface plasmon resonance principle mostly adopt the prism coupling structure. This type of sensor has complex structure, large volume, and high production cost, so it is difficult to form a wide application in industrial production; although there are currently multi-layer metal alternating film systems Surface plasmon resonance sensors have emerged, but most of them are single-channel structures. In the sensing and detection of biochemical samples, they are easily affected by factors such as temperature or the change of the refractive index of the sample solution body and sample volatilization. The sensors do not have compensation capabilities. poor accuracy
However, the existing dual-channel optical fiber sensors based on the principle of surface plasmon resonance mostly use the method of modulation wavelength by coating, the modulation method is single, and the detection accuracy is poor.

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  • Self-accurate fiber-optic surface plasmon resonance biochemical detection sensor with dual modulation modes

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Embodiment Construction

[0010] The specific embodiments of the present invention will be described in detail below in conjunction with the technical solutions and accompanying drawings.

[0011] The invention uses surface plasmon resonance as the sensing principle, and the generation of this effect depends on a wide-spectrum light source, and aims to realize the sensing and detection of wavelength modulation and intensity modulation in the optical fiber. In order to enhance the signal strength and optimize the sensing performance, the fiber used to make the sensor chooses a large-aperture multimode fiber. The optical fiber adopted in the present invention is a large-aperture plastic-clad optical fiber with a core diameter, cladding layer, and coating layer diameters of 400 μm, 430 μm, and 730 μm respectively, and a numerical aperture of 0.37.

[0012] The preparation process of the present invention is as follows:

[0013] (1) First, take a 60mm long section of plastic-clad multimode optical fiber, ...

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Abstract

The invention provides a double-modulation-mode self-precision optical fiber surface plasma resonance biochemical detection sensor and belongs to the technical field of optical fiber sensing. The sensor adopts a terminal reflective sensing structure. According to the invention, the end face of a fiber core of a plastic-clad multimode fiber with the core diameter being 400-600 m and numerical aperture being not less than 0.24 is polished, and the polished fiber core end-face undergoes sputtering of more than 200 nm of a silver film to form a reflecting mirror surface; and two sections of coating layers and cladding layers on the multimode fiber are stripped to form two sensing channels of 5-10 mm long. Gold nano-spheres are fixed on the surface of one sensing channel, and silver-ITO two-layered films are sputtered in the order of silver-ITO onto the surface of the other sensing channel, wherein thickness of the silver layer is 35-45 nm, and thickness of the ITO layer is 5-15 nm. By a simple sputter coating technology and a layer-by-layer self-assembly method, double-modulating signal demodulation is realized, and precision influence generated by a single modulation mode is avoided.

Description

technical field [0001] The invention belongs to the technical field of optical fiber sensing, and relates to a dual-modulation optical fiber surface plasma resonance biochemical detection sensor with self-accurate function. Background technique [0002] At present, the dual-channel biochemical sensors using the surface plasmon resonance principle mostly adopt the prism coupling structure. This type of sensor has complex structure, large volume, and high production cost, so it is difficult to form a wide application in industrial production; although there are currently multi-layer metal alternating film systems Surface plasmon resonance sensors have emerged, but most of them are single-channel structures. In the sensing and detection of biochemical samples, they are easily affected by factors such as temperature or the change of the refractive index of the sample solution body and sample volatilization. The sensors do not have compensation capabilities. Accuracy is poor. Ho...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/59
CPCG01N21/59G01N2021/5903
Inventor 李丽霞彭伟卢梦迪谢灵骁
Owner DALIAN UNIV OF TECH