Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A method for improving the leaching rate of polysaccharides in Dendrobium officinale

A technology of dendrobium candidum and leaching rate, which is applied in the field of traditional Chinese medicine preparation, can solve the problems of insufficient depth and breadth of development and utilization of natural active substances, polysaccharide components can not be fully absorbed by the human body, and stay in the overall function of dendrobium candidum, so as to improve bioavailability High degree, easy digestion and absorption, short processing time

Active Publication Date: 2018-04-03
上海米塔星科技服务有限公司
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are a number of products and patents related to Dendrobium candidum in my country. The State Food and Drug Administration has included more than 50 kinds of health products using Dendrobium as raw materials, of which 42 kinds use Dendrobium as the main raw material, such as Tiepi Fengdou Granules, Dendrobium buccal tablets, Dendrobium candidum oral liquid, etc., but most of these products stay on the overall function of Dendrobium candidum, and the depth and breadth of the development and utilization of natural active substances are far from enough
[0004] As the fresh products of Dendrobium candidum should not be stored for a long time, although the storage time can be extended after drying, the sensory indicators will deteriorate, and it is not very convenient to eat, especially the main active ingredient polysaccharide, which is mostly insoluble or only slightly soluble in water In addition, the viscosity of the polysaccharide component is relatively high, and it cannot be micronized by ordinary crushing methods, so that the polysaccharide component cannot be fully absorbed by the human body, and the waste is relatively large, resulting in a decrease in its efficacy
In addition, the existing Dendrobium officinale products are mostly in the form of flakes or pills. Due to the large particles, they disperse slowly after entering the stomach, which is not conducive to the absorption of polysaccharides by the human body. At the same time, it is inconvenient to eat. Most users take it as medicine , not conducive to large-scale promotion

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0032] (1) Preparation of polysaccharide reference substance solution: Take an appropriate amount of anhydrous glucose reference substance, weigh it accurately, add water to make a glucose solution containing 90 μg per 1 ml, and obtain it.

[0033] (2) Preparation of the standard curve: Precisely measure 0.2ml, 0.4ml, 0.6ml, 0.8ml, 1.0ml of the reference solution, put them in 10ml test tubes with stoppers, and add water to make up to 1.0ml. Accurately add 1ml of 5% phenol solution (prepared for use), shake well, then precisely add 5ml of sulfuric acid, shake well, heat in boiling water bath towel for 20 minutes, take it out, cool in ice bath for 5 minutes, use the corresponding reagent as a blank, use ultraviolet light Visible spectrophotometry, the absorbance is measured at a wavelength of 488nm, with the absorbance as the ordinate and the concentration as the abscissa, draw a standard curve.

[0034] (3) Preparation of the test solution: Take about 0.3g of the powder of this...

Embodiment 1

[0045]A, fresh dendrobium candidum strips are cleaned and dried;

[0046] B, the fresh strips of Dendrobium officinale of step A are placed in a drying box, dried at 100° C. for 3.75 hours, so that its moisture content is 23%, and cut into short strips of 4.5 centimeters;

[0047] C, the dendrobium candidum short strips of step B are obtained by microwave puffing and breaking; the process conditions of the microwave puffing and breaking are power 750w, and the time of expanding and breaking is 30 seconds, so that the expanded and broken products are obtained;

[0048] D. After cooling the puffed broken wall product in step C for 15 minutes, it is crushed (passed through a 200-mesh sieve) and packaged.

[0049] E. Add 60 ml of water to the Dendrobium officinale powder (10 grams) obtained in step D and extract at 93° C. for 4 times, each time for 2 hours, combine the extracts, filter and concentrate to obtain an extract with a relative density of 1.2;

[0050] F. After drying t...

Embodiment 2

[0053] A, fresh dendrobium candidum strips are cleaned and dried;

[0054] B, the fresh strips of Dendrobium candidum of step A are placed in a drying box, dried at 105°C for 3.5 hours, so that its moisture content is 15%, and cut into short strips of 4.0 cm;

[0055] C, the dendrobium candidum short strips of step B are obtained by microwave puffing and breaking the wall; the process conditions of the microwave puffing and breaking are power 700w, and the time of expanding and breaking the wall is 35 seconds, so as to obtain the expanded and broken wall product;

[0056] D. After cooling the puffed broken wall product in step C for 15 minutes, it is crushed (passed through a 300-mesh sieve) and packaged.

[0057] E. Add 80 ml of water to the Dendrobium officinale powder (10 grams) obtained in step D and extract 3 times at 100° C. for 3 hours each time, combine the extracts, filter and concentrate to obtain an extract with a relative density of 1.3;

[0058] F. After drying t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for increasing the leaching rate of polysaccharide components in dendrobium candidum. The method includes the steps of preprocessing, extraction and post-processing. The method specifically includes the steps that fresh dendrobium candidum strips are cleaned, air-dried and dried for 3.5-4.0 h at the temperature of 95-105 DEG C till the water content is 15-30%, the fresh dendrobium candidum strips are cut into short strips a with the length being 4.0-5.0 cm, a dendrobium candidum pre-extraction material b is obtained after swelling cell disruption is conducted on the short strips a and the short strips a are smashed and screened through a sieve with 100-300 meshes, water with the weight 4-8 times that of the pre-extraction material b of dendrobium candidum is added into the pre-extraction material b, the pre-extraction material is extracted three to four times at the temperature of 80-100 DEG C, each time extraction lasts for 1-3 hours, and extraction solutions are combined, filtered and concentrated to obtain an extract c with the relative density being 1.1-1.3; the extracted extract c is dried, smashed and screened to obtain a target extract. Production equipment investment is little, technological operation is easy, conditions are easy to meet, energy consumption in the preparation process is low, cost is low, processing is convenient, and reagents in use are free of toxin and harm, safe and environmentally friendly. The polysaccharide components in a prepared dendrobium candidum product are easy to leach, and the leaching rate of the polysaccharide components in the dendrobium candidum is increased.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparation, and in particular relates to a method for increasing the leaching rate of polysaccharide components in dendrobium officinale. Background technique [0002] Dendrobium officinale is a plant of the genus Dendrobium in the family Orchidaceae ( Dendrobium officinale Kimura et Migo), named for its iron-green skin. Dendrobium plants can be divided into dozens of varieties such as Tiepi, Nobile, Huoshan, Huangcao, Huancao, and Horsewhip according to their shape and origin. Among them, Dendrobium candidum is the most precious. The fresh stems of Dendrobium candidum can be eaten directly, stewed in soup, made into tea, or soaked in wine, and are usually processed into dry products, such as Tiepi Fengdou and Dendrobium candidum functional drinks. In recent years, more and more high-grade health products are produced from Dendrobium candidum, which are sold well in Europe...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08B37/00
CPCC08B37/00C08B37/0003
Inventor 黄相中彭金辉郭俊明李婷婷
Owner 上海米塔星科技服务有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com