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Traditional Chinese medicine hemostatic powder and preparation method thereof

A technology of hemostatic powder and traditional Chinese medicine, which is applied in medical formula, blood diseases, powder delivery, etc. It can solve the problems of tissue necrosis, tourniquet easy to fall off, congestion, etc., and achieve the effect of safe use and shortening bleeding time

Inactive Publication Date: 2016-06-01
SUZHOU BEC BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oxidized cellulose, fibrin glue and synthetic glue point pricking have been used for local hemostasis trials; molecular sieves and chitosan are the latest generation of local hemostasis trials, and their effects and safety are currently being studied; recombinant Activated coagulation factor VII (FVIIa) is the most ideal hemostatic agent for trauma hemostasis, but its safety for trauma patients has yet to be investigated through multiple randomized controlled experiments.
[0003] The traditional methods of hemostasis mainly include suturing, pressing and dressing. The main hemostatic products include first aid kits, four-head bands, hemostatic gauze, tourniquets and bandages. The main method, but there will be great defects during or after use, so it is greatly limited in clinical application
For example, suture hemostasis is very effective for traumatic bleeding of soft tissues and large blood vessels, but the effect of hemostasis on solid organs with high fragility and rich blood flow is not ideal, and it is very easy to cause needle holes or hemorrhagic tissue damage. This affects the normal functions of the kidneys, brain and other substantial organs; pressing to stop bleeding requires pressing the capillaries for tens of minutes to promote the aggregation of platelets, which is the most direct way to stop bleeding on the body surface. A lot of bleeding but the hemostatic effect is not ideal
There are also many defects in the process of using the tourniquet: if the tourniquet is not properly treated for the wound or the time and pressure are not correctly grasped, it may cause pain near the wound, nerve damage, and even tissue necrosis in severe cases; For special and relatively common trauma, such as irregular shape, deep, narrow, arterial rupture and other wounds, the hemostatic effect is not good; the tourniquet is easy to fall off, causing secondary bleeding; the use of the tourniquet will induce soft tissue around the surgical wound. Reactive hyperemia, significant drop in oxygen content, etc.
It can be seen that traditional hemostatic materials can no longer meet the clinical needs of safe hemostasis in modern surgery and emergency trauma hemostasis. The shortcomings of these hemostasis methods need other new hemostatic materials to make up for

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Traditional Chinese medicine hemostatic powder, the components and the mass parts of each component are as follows: 10-20 parts of Baiji, 5-10 parts of Sophora japonica, 2-8 parts of Puhuang, 3-6 parts of Agrimony, 2-6 parts of Xue Yu Charcoal , 8~20 parts of mugwort leaves, 2~5 parts of Burnet, 2~8 parts of palm, 3~6 parts of Panax notoginseng, 1~3 parts of mint, 10~15 parts of whey protein, 5~10 parts of collagen.

[0020] The preparation method comprises the steps of:

[0021] 1) Mix Baiji, Sophora japonica, Puhuang, Agrimony, Xueyu charcoal, Artemisia argyi, Burnet, palm, Panax notoginseng and mint in proportion by mass, and grind into powder;

[0022] 2) Add whey protein and collagen to the powder in step 1), stir evenly at a speed of 120 rpm, and dry at 55°C for 15 hours to obtain a traditional Chinese medicine hemostatic powder.

Embodiment 2

[0024] Traditional Chinese medicine hemostatic powder, the components and the mass parts of each component are as follows: 10-20 parts of Baiji, 5-10 parts of Sophora japonica, 2-8 parts of Puhuang, 3-6 parts of Agrimony, 2-6 parts of Xue Yu Charcoal , 8~20 parts of mugwort leaves, 2~5 parts of Burnet, 2~8 parts of palm, 3~6 parts of Panax notoginseng, 1~3 parts of mint, 10~15 parts of whey protein, 5~10 parts of collagen.

[0025] The preparation method comprises the steps of:

[0026] 1) Mix Baiji, Sophora japonica, Puhuang, Agrimony, Xueyu charcoal, Artemisia argyi, Burnet, palm, Panax notoginseng and mint in proportion by mass, and grind into powder;

[0027] 2) Add whey protein and collagen to the powder in step 1), stir evenly at a speed of 120 rpm, and dry at 55°C for 15 hours to obtain a traditional Chinese medicine hemostatic powder.

Embodiment 3

[0029] Traditional Chinese medicine hemostatic powder, the components and the mass parts of each component are as follows: 15 parts of Baiji, 5 parts of Sophora japonica, 5 parts of Puhuang, 4 parts of Agrimony, 5 parts of Xue Yu Charcoal, 15 parts of Artemisia argyi, 3 parts of Burnet, 5 parts palm, 4 parts Panax notoginseng, 2.5 parts mint, 12 parts whey protein, 6 parts collagen.

[0030] The preparation method comprises the steps of:

[0031] 1) Mix Baiji, Sophora japonica, Puhuang, Agrimony, Xueyu charcoal, Artemisia argyi, Burnet, palm, Panax notoginseng and mint in proportion by mass, and grind into powder;

[0032] 2) Add whey protein and collagen to the powder in step 1), stir evenly at a speed of 120 rpm, and dry at 55°C for 15 hours to obtain a traditional Chinese medicine hemostatic powder.

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PUM

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Abstract

The invention discloses traditional Chinese medicine hemostatic powder and a preparation method thereof. The traditional Chinese medicine hemostatic powder is prepared from, by mass, 10-20 parts of common bletilla pseudobulb, 5-10 parts of sophora japonica, 2-8 parts of typhae pollen, 3-6 parts of agrimonia pilosa ledeb, 2-6 parts of crinis carbonisatus, 8-20 parts of folium artemisiae argyi, 2-5 parts of sanguisorba officinalis, 2-8 parts of trachycarpus fortunei, 3-6 parts of panax notoginseng, 1-3 parts of mint, 10-15 parts of whey protein and 5-10 parts of collagen. The traditional Chinese medicine hemostatic powder is formed by compositing hemostatic traditional Chinese medicine, is used for hemorrhagic wounds, can quickly stop bleeding, greatly shortens bleeding time, and is safe to use and free of side effects.

Description

technical field [0001] The invention belongs to the technical field of medical hemostatic materials, and in particular relates to a traditional Chinese medicine hemostatic powder and a preparation method thereof. Background technique [0002] Bleeding remains the leading cause of death in trauma patients. At present, the effective control method for aortic bleeding only stays on the operating table, but for field or acute trauma bleeding patients, the best treatment time is often missed due to excessive blood loss on the way to the emergency room after bleeding, so , How to effectively control bleeding in the first time has become the most challenging and important task at present. Compared with some traditional methods of surgical control of hemostasis, some advanced hemostatic materials and test punctures have recently appeared, which can be used for field hemostasis or emergency life-saving hemostasis. Oxidized cellulose, fibrin glue and synthetic glue point pricking ha...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61K36/898A61K9/14A61P7/04
CPCA61K35/36A61K9/0014A61K9/14A61K36/258A61K36/282A61K36/489A61K36/534A61K36/73A61K36/739A61K36/88A61K36/889A61K36/898A61K38/38A61K38/39A61K2300/00
Inventor 李苏杨李文遐徐勤霞
Owner SUZHOU BEC BIOLOGICAL TECH
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