Rabbit Traumatic Osteoarthritis Model Maker

Abstract

The invention relates to a domestic rabbit traumatic osteoarthritis model making device. An impact head is arranged at one end of an impact rod of an impact unit in a detachable mode, and a sleeve movably sleeves the outer side of the impact rod; a spring covers the outer side of the impact rod which is located in the sleeve; when the spring is at a natural length, a shielding sheet clings to a second baffle plate; when the domestic rabbit traumatic osteoarthritis model making device is used, the relative positions and included angles of the impact unit, a connecting unit and a leg wrapping unit are regulated and fixed, when the rear end of the impact rod is pulled by external force, the impact rod and the shielding sheet are integrally moved backwards and the spring becomes shrunk, and meanwhile, the shielding sheet and the second baffle plate are separated; the spring, after being released, can drive the impact head of the impact rod to impact upon an object in the front, so that a controllable operation over a cartilage injury degree can be achieved by regulating the strength of the exerted external force; various osteoarthritis models are comparable; and the domestic rabbit traumatic osteoarthritis model making device is good in experimental effect and high in experimental data reliability.

Description

technical field [0001] The invention belongs to a biological trauma device for animal experiments, in particular to a rabbit traumatic osteoarthritis model maker. Background technique [0002] At present, the pathogenesis of osteoarthritis is not yet clear, and the treatment of osteoarthritis is still a worldwide problem. A large number of medical workers are conducting in-depth research on this disease. Due to ethical constraints, it is often impossible to conduct research on patients with osteoarthritis in medical research, so animal research occupies a very important position. [0003] The first step in animal research on osteoarthritis is to make osteoarthritis models, among which the rabbit traumatic osteoarthritis model is the most classic and is widely used in osteoarthritis research. There are two main methods for making traumatic osteoarthritis models in rabbits: (1) cutting off the cruciate ligament of the knee joint of the rabbit’s hind leg to cause joint instabi...

AI Technical Summary

Problems solved by technology

However, the current routine operation only uses instruments such as blades or bone drills to violently damage the cartilage, and it is impossible to control the degree of cartilage damage.

Different degrees of cartilage damage lead to significant differences in the degree of lesions in osteoarthritis models, which will directly affect the comparability of different osteoarthritis models and affect the experimental results.

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