Heart failure event prediction using classifier fusion

An event and predictor technology, applied in instruments, applications, cardiac catheterization, etc., can solve problems such as reducing the efficiency of cardiac pumping, improve prognosis and patient outcomes, reduce health care costs, and ensure timely treatment.

Inactive Publication Date: 2016-07-20
CARDIAC PACEMAKERS INC
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Asynchronous contraction of the left and right ventricles also reduces the pumping efficiency of the heart

Method used

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  • Heart failure event prediction using classifier fusion
  • Heart failure event prediction using classifier fusion
  • Heart failure event prediction using classifier fusion

Examples

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Embodiment Construction

[0038] Disclosed herein are systems, devices, and methods for detecting events indicative of exacerbation of HF, such as events of HF decompensation, or for identifying patients at high risk of developing future events associated with exacerbation of HF. HF event detection or HF risk stratification may be performed using, for example, physiological signals sensed from one or more physiological sensors associated with a dynamic medical device (eg, an implanted cardiac device, etc.). The physiological signal is selectively available to two or more partial predictors, wherein each of the two or more partial predictors is configured to calculate a partial risk index indicative of a patient The likelihood of developing a prognostic physiological event indicative of or associated with exacerbation of HF. Classifier fusion can then be used to combine the partial risk indices and generate a detection call for HF exacerbation, or to predict the risk of future HF events, thereby enablin...

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Abstract

Systems and methods for detecting a heart failure (HF) event indicative of worsening of HF, or for identifying patient at elevated risk of developing future HF event, are described. The system and methods can detect an HF event or predict HF risk using a multitude of fusion algorithms or classifiers, each employing one or more physiologic sensor signals. A system can comprise two or more partial predictor circuits each can adaptively generate a dynamic computational model (DCM). Each partial predictor circuit can determine a partial risk index indicating a likelihood of the patient developing a precursor physiologic event indicative or correlative of a future HF event. The system can include a prediction fusion circuit that can combine the partial risk indices and generate a composite risk indicator for detecting or predicting a likelihood of the patient developing a future HF event.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of priority under 35 U.S.C § 119(e) of U.S. Provisional Patent Application Serial No. 61 / 912,568, filed December 6, 2013, which is hereby incorporated by reference in its entirety . technical field [0003] The present invention relates to medical devices and, more particularly, to systems, devices and methods for detecting and monitoring progression of heart failure. Background technique [0004] Congestive heart failure (CHF) is a major health problem and affects more than five million people in the United States alone. CHF is the loss of the heart's pumping energy, resulting in an inability to deliver enough blood to meet the demands of surrounding tissues. CHF patients typically have an enlarged heart due to weakened heart muscle, resulting in reduced contractility and poor blood output from the heart. [0005] CHF is usually a chronic state, but can occur suddenly. It can af...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/0205G06F19/00A61N1/365G16H40/63G16H50/30
CPCA61B5/7267A61B5/0002A61B5/01A61B5/02028A61B5/02055A61B5/0215A61B5/02405A61B5/0826A61B5/145A61B5/14532A61B5/14542A61B5/14546A61N1/36521A61N1/3655A61N1/36557A61N1/36564A61N1/36585A61N1/36592A61N1/36571G16H50/30G16H50/20A61B5/0205A61B5/024A61B5/0816A61B5/7275A61B7/00G16H40/63A61B5/349A61B5/053A61B5/1118A61B5/1121A61B5/7264A61B5/7282A61B7/04
Inventor 安琪盖伊·R·霍特森普拉莫德辛格·希拉辛格·塔库尔张仪
Owner CARDIAC PACEMAKERS INC
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