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Traditional Chinese medicine for treating breast cystic hyperplasia and preparation method thereof

A technology of breast cystic hyperplasia and traditional Chinese medicine, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. effect of reaction

Inactive Publication Date: 2016-09-21
周茂军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hyperplasia and dysplasia coexist in this disease, and there is a risk of malignant transformation

Method used

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  • Traditional Chinese medicine for treating breast cystic hyperplasia and preparation method thereof
  • Traditional Chinese medicine for treating breast cystic hyperplasia and preparation method thereof

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Experimental program
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Effect test

preparation example Construction

[0047] When the dosage form of the Chinese medicine is syrup, its preparation method may further comprise the steps:

[0048] In the first step, mix Zhanlongcao, Yanqinglan, Xiaoerxiancao, Water Wenghua, Shanxiaoju and Shulongcao according to the stated ratio, and add 4 to 6 times the alcohol concentration of the mixture to 80%~ 90% ethanol, heated and refluxed for 2 to 4 times, refluxed for 2 hours to 3 hours each time, combined the extracts, centrifuged with a tube centrifuge to remove impurities, and put the extracted extracts at 60°C to 70°C Concentrate under reduced pressure to a liquid medicine with a relative density of 1.05-1.10 at 60°C, dry the concentrated liquid with a spray dryer, and then crush it into 100-200 meshes to obtain a dry powder;

[0049] In the second step, mix Niu Xixi, Polygonum sylvestris, Cottongrass, Roller worm, Geranium japonica and Mao berry according to the stated proportions, grind them into powder, use ethanol with an alcohol concentration o...

Embodiment 1

[0060] Embodiment 1: syrup

[0061] Take 260g Zhanlongcao, 160g Yanqinglan, 180g Xiaoerxiancao, 120g Water Wenghua, 140g Shanxiaoju, 260g Treeclimbing Dragon, 300g Niu Xixi, 150g Capsicum Polygonum, 160g Sorrelwort, 270g Rolling Mountain Insect, 220g leaf tree, 200g strawberry, 240g smile flower, 100g cucumber kernel grass, 280g laurel, 200g black trigonum, 180g grass dragon root and 270g oil orange root.

[0062] Its preparation method comprises the following steps:

[0063] In the first step, mix Zhalongcao, Yanqinglan, Xiaoerxiancao, Water Wenghua, Shanxiaoju and Shulong in the stated ratio, and add ethanol with an alcohol concentration of 90% that is 5 times that of the mixture, Heated and refluxed for 4 times, refluxed for 2 hours each time, combined the extracts, centrifuged with a tube centrifuge to remove impurities, and concentrated the removed extracts under reduced pressure at 65°C to 60°C with a relative density of 1.08 The liquid medicine after concentration is ...

Embodiment 2

[0067] Embodiment 2: oral liquid

[0068] Take 280g Zhanlongcao, 130g Yanqinglan, 210g Xiaoerxiancao, 90g Water Wenghua, 170g Shanxiaoju, 220g Tree Climbing Dragon, 320g Niu Xixi, 110g Polygonum sativa, 200g Sorrelwort, 240g Rolling Mountain Insect, 260g of leaf tree, 160g of strawberry, 210g of smiling flower, 130g of cucumber kernel grass, 260g of laurel, 220g of black trigonum, 150g of grass dragon root and 300g of oil orange root.

[0069] Its preparation method comprises the following steps:

[0070] The first step is to mix Zhanlongcao, Yanqinglan, Xiaoerxiancao, Water Wenghua, Shanxiaoju, Climbing Treelong, Niuxixi, Spicy Polygonum and Cottonwort, and add 4 times the amount of alcohol relative to the mixture. Reflux extraction with 60% ethanol twice, each time for 2.5 hours, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.31 at 70°C, and set aside;

[0071] In the second step, mix the remaining raw medicinal material...

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Abstract

The invention provides a traditional Chinese medicine for treating breast cystic hyperplasia and a preparation method thereof. The traditional Chinese medicine comprises the following Chinese herbal medicines of herb of argun groundsel, dracocephalum rupestre hance, haloragis micrantha, flower of operculate cleistocalyx, glycosmis pentaphylla, rhaphidophora decursiva, patience dock root, red-knees herb, sowthistle tasselflower herb, glomeris nipponica kishida, lindera communis, rubus parvifolius, bridal wreath, polygala japonica, caulis et folium plucheae, sparganium stoloniferum, ludwigia hyssopifo-lia (G.Don) exekk and root of emblic leafflower. The traditional Chinese medicine has the beneficial effects that by combining with the conventional western medicine method, the breast cystic hyperplasia can be treated; the convenience in use is realized, the treatment effect is effectively improved, the effective rate and curative rate are increased, any toxic or side effect is avoided, the treatment effect is quick, the easiness in reoccurrence is avoided after recovery, the adverse effect of western medicines is reduced, and the preparation technology is simple.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine for treating cystic hyperplasia of the breast and a preparation method thereof. Background technique [0002] Cystic hyperplasia of the breast (disease of the breast cystic hyperplasia, BCH) is a disease characterized by cysts formed by highly dilated breast lobules, small ducts, and Songpu ducts, accompanied by some other structural abnormalities. Hyperplasia and dysplasia coexist in this disease, and there is a risk of malignant transformation. Cystic hyperplasia is completely pathological, and histological changes are irreversible. Breast hyperplasia is cystic hyperplasia of the breast, which refers to hyperplasia of breast epithelium and fibrous tissue, structural degeneration of breast tissue ducts and lobules, and progressive connective tissue growth. The main cause of the disease is endocrine hormone imbalanc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/902A61K9/10A61K9/08A61P15/14A61K35/63
CPCA61K36/902A61K9/0095A61K35/63A61K36/185A61K36/28A61K36/47A61K36/53A61K36/54A61K36/61A61K36/69A61K36/70A61K36/704A61K36/73A61K36/75A61K36/888A61K47/26A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 周茂军徐国成程相标
Owner 周茂军
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