DNA (Deoxyribose Nucleic Acid) and protein level mutation analysis system

An analysis system and protein technology, which is applied in the field of DNA and protein level mutation analysis systems, and can solve the problems of interpretation and interpretation of results that are difficult to parse.

Inactive Publication Date: 2016-10-12
WANKANGYUAN TIANJIN GENE TECH CO LTD
View PDF0 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since there is no unified standard for the naming of gene mutations in a large number of previous studies, it is difficult to further annotate and interpret the results of the analysis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • DNA (Deoxyribose Nucleic Acid) and protein level mutation analysis system
  • DNA (Deoxyribose Nucleic Acid) and protein level mutation analysis system
  • DNA (Deoxyribose Nucleic Acid) and protein level mutation analysis system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0026] It should be noted that, in the case of no conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other.

[0027] The present invention will be described in detail below with reference to the accompanying drawings and examples.

[0028] Principle explanation of the present invention:

[0029] The mapping of different levels of mutations is actually the position positioning and calculation of mutation results at different levels. For different levels of mutations, different mapping methods and steps are required. The present invention mainly aims at the situation that the mutation naming at different levels cannot be directly applied in a unified manner, and maps the relationship of the mutation results at all levels to facilitate the further use of the mutation results.

[0030] Such as figure 1 As shown, the specific steps are as follows:

[0031] First, an index of gene transcript structure and sequence as w...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a DNA (Deoxyribose Nucleic Acid) and protein level mutation analysis system, which comprises a reading and indexing judgment module and a mapping module, wherein the reading and indexing judgment module is used for readubg a gene mutation file, carrying out formatting processing on the gene mutation file to obtain a standard name, indexing a transcript sequence, gene information and gene transcript annotation information, constructing an amino acid codon corresponding correlation chart, and judging a mutation generation level and mutation mode, and judging whether mutation naming is protein level mutation or genome DNA level mutation or CDS (Coding Sequence) coding region mutation; and the mapping module is used for independently entering different level mutation mapping flows according to the judgment result of the reading and indexing judgment module to obtain the mapping relationship of three types of mutation naming. The system undertakes the phenotype relevant gene mutation and the polymorphic site of literature mining, and outputs the mapping relationship of various types of mutation naming so as to achieve a purpose of finishing the correspondence and the like of the gene mutation and the polymorphic sites of the pathopoiesia variation and the sequencing identification of the literature mining.

Description

technical field [0001] The invention belongs to the field of gene information data processing, in particular to a DNA and protein level mutation analysis system. Background technique [0002] In the more than 50 years since Watson and Crick discovered the double helix structure of DNA, the exploration of genetic variation has played an important role in the study of the occurrence, development, prevention and treatment of human diseases. Opened up a wide space. In recent years, from microarray chips, Sanger sequencing to the current high-throughput sequencing, with the advancement of technology, more and more gene variations and polymorphic sites have been detected. They reveal the mechanisms of diseases and many phenotypes at the molecular level, bringing new hope to unravel the mysteries of life and conquer diseases. [0003] However, the gene mutations and polymorphic sites identified by different researchers lack a unified expression in naming. For example, the tumor s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/18
CPCG16B20/00
Inventor 薛成海龚永辉刘宇
Owner WANKANGYUAN TIANJIN GENE TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap