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Medicine composition for treating postoperative colon cancer and preparation method thereof

A composition and technology for colon cancer, which can be used in drug combinations, pharmaceutical formulations, active ingredients of heterocyclic compounds, etc., and can solve problems such as non-cross-tolerance

Inactive Publication Date: 2016-10-26
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Repeated injections can produce tolerance, but no cross-resistance with bacterial pyrogens

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1: Pharmaceutical composition and preparation method of traditional Chinese medicine combined with chemotherapy for postoperative colon cancer

[0033] The composition and parts by weight of the raw material drug of the pharmaceutical composition of traditional Chinese medicine combined with chemotherapy to treat postoperative colon cancer are: Guya 2900g, Potentilla clover 1200g, castor bean 1900g, five-finger peach 3200g, hydroxyemodin 37g, ash bark resin alcohol 50g, ethyl erucate 33g;

[0034] Preparation:

[0035] (1) Take grain buds, Potentilla clover, castor bean, five-finger peach, hydroxyemodin, alkoresinol, and ethyl erucate according to the ratio of raw materials, mix well, and use ethanol with a concentration of 40% by weight as a solvent , at 52°C for warm soaking and extraction, the number of extractions is 7 times, each extraction time is 25 hours, and the amount of solvent used each time is 41 times the total weight of the raw material drug, and...

Embodiment 2

[0038] Example 2: Pharmaceutical composition and preparation method of traditional Chinese medicine combined with chemotherapy for postoperative colon cancer

[0039] Composition and parts by weight of the crude drug of the medicinal composition of traditional Chinese medicine combined with chemotherapy to treat postoperative colon cancer are: Guya 2850g, Potentilla clover 1250g, castor bean 1850g, five-finger peach 3250g, hydroxyemodin 32g, ash bark resin alcohol 55g, ethyl erucate 28g;

[0040] Preparation:

[0041] (1) Take grain buds, Potentilla clover, castor bean, five-finger peach, hydroxyemodin, alkoresinol, and ethyl erucate according to the ratio of raw materials, mix well, and use ethanol with a concentration of 40% by weight as a solvent , at 52°C for warm soaking and extraction, the number of extractions is 7 times, each extraction time is 25 hours, and the amount of solvent used each time is 41 times the total weight of the raw material drug, and filtered to obt...

Embodiment 3

[0044] Example 3: Pharmaceutical composition and preparation method of traditional Chinese medicine combined with chemotherapy for postoperative colon cancer

[0045] Composition and parts by weight of the crude drug of the medicinal composition of traditional Chinese medicine combined with chemotherapy to treat postoperative colon cancer are: Guya 2950g, Potentilla clover 1150g, castor bean 1950g, five-finger peach 3150g, hydroxyemodin 42g, ash bark resin alcohol 45g, ethyl erucate 38g;

[0046] Preparation:

[0047](1) Take grain buds, Potentilla clover, castor bean, five-finger peach, hydroxyemodin, alkoresinol, and ethyl erucate according to the ratio of raw materials, mix well, and use ethanol with a concentration of 40% by weight as a solvent , at 52°C for warm soaking and extraction, the number of extractions is 7 times, each extraction time is 25 hours, and the amount of solvent used each time is 41 times the total weight of the raw material drug, and filtered to obta...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating postoperative colon cancer with traditional Chinese medicine combined with chemotherapy and a preparation method thereof. Piresinol and ethyl erucate are used as raw materials, prepared in a proportioned manner, and can be made into various dosage forms according to conventional preparation processes. The curative effect of traditional Chinese medicine combined with chemotherapy on postoperative colon cancer is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating postoperative colon cancer with traditional Chinese medicine combined with chemotherapy and a preparation method thereof. Background technique [0002] Colon cancer refers to malignant tumors that originate in the epithelium of the colonic mucosa, and its incidence rate accounts for 8%-12% of all tumor patients. Epidemiology shows that at present, with the improvement of people's living standards, great changes have taken place in living habits and diet structure, and the incidence of colon cancer is increasing year by year, which has become one of the diseases that seriously threaten the health and life of our people. At present, the clinical treatment of colon cancer is mainly based on surgical resection, combined with chemotherapy, radiotherapy and other means, but some patients are prone to local recur...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P35/00A61K31/122A61K31/34A61K31/231
CPCA61K36/899A61K31/122A61K31/231A61K31/34A61K36/47A61K36/60A61K36/73A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 庞大坤孔倩倩
Owner JINAN XINGYI MEDICAL TECH
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