Externally used traditional Chinese medicine composition and preparation which are capable of avoiding allergy and relieving itching, and preparation method thereof

A technology of composition and skin care composition, which is applied in the direction of medical preparations containing active ingredients, drug combinations, skin care preparations, etc., to achieve the effects of easy acceptance, strong inhibitory effect, and simple preparation method

Active Publication Date: 2016-11-30
北京国济众芳中医药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In addition, there are many users whose facial skin has weak stratum corneum, which makes the capillaries easier to contact and perceive the changes in the exte

Method used

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  • Externally used traditional Chinese medicine composition and preparation which are capable of avoiding allergy and relieving itching, and preparation method thereof
  • Externally used traditional Chinese medicine composition and preparation which are capable of avoiding allergy and relieving itching, and preparation method thereof
  • Externally used traditional Chinese medicine composition and preparation which are capable of avoiding allergy and relieving itching, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0049] Embodiment 1 Preparation of the traditional Chinese medicine composition of the present invention

[0050] (1) Weigh the crude drug according to the following proportions, pulverize to 60 meshes, and mix uniformly;

[0051] Raspberry 65g, Ligustrum lucidum 35g, Haematococcus pluvialis 40g, Cardamom 50g, Cherry Blossom 20g.

[0052] (2) extract with 95% ethanol by volume, the mass volume ratio g / mL of crude drug and ethanol is 1:15, and extract by heating and stirring at 70°C for 1 hour to obtain an extract;

[0053] (3) the extract obtained in step (2) is cooled to room temperature, and filtered with 120 meshes to obtain a filtrate;

[0054] (4) it is 0.5g / mL that the filtrate is concentrated to the crude drug concentration by rotary evaporation of ethanol to obtain concentrate;

[0055] (5) Add the original ethanol amount of 1,3-butanediol to the concentrate to mix evenly, spread a 1.2 μm filter plate in a Buchner funnel for vacuum filtration, and collect the filtrat...

Example Embodiment

[0056] Embodiment 2 The preparation of the traditional Chinese medicine composition of the present invention

[0057] (1) Weigh the crude drug according to the following proportions, pulverize to 70 meshes, and mix well;

[0058] Raspberry 40g, Ligustrum lucidum 20g, Haematococcus pluvialis 30g, Cardamom 45g, Cherry Blossom 15g.

[0059](2) extract with 70% ethanol by volume, the mass volume ratio g / mL of crude drug and ethanol is 1:10, and extract with heating and stirring at 60°C for 1.5 hours to obtain an extract;

[0060] (3) the extract obtained in step (2) is cooled to room temperature, and filtered with 100 meshes to obtain a filtrate;

[0061] (4) be 0.3g / mL by filtrate rotary evaporation ethanol concentration to crude drug concentration, obtain concentrate;

[0062] (5) Add the original ethanol amount of 1,3-butanediol to the concentrate to mix evenly, spread a 1.5 μm filter plate in a Buchner funnel for vacuum filtration, and collect the filtrate.

Example Embodiment

[0063] The preparation of embodiment 3 Chinese medicine composition of the present invention

[0064] (1) Weigh the crude drug according to the following proportions, pulverize to 80 mesh, and mix well;

[0065] Raspberry 70g, Ligustrum lucidum 40g, Haematococcus pluvialis 10g, Cardamom 30g, Cherry Blossom 10g.

[0066] (2) extract with 60% ethanol by volume, the mass volume ratio g / mL of crude drug and ethanol is 1:20, and extract with heating and stirring at 50°C for 2 hours to obtain an extract;

[0067] (3) the extract obtained in step (2) is cooled to room temperature, and filtered with 80 meshes to obtain a filtrate;

[0068] (4) it is 0.2g / mL that the filtrate is concentrated to the crude drug concentration by rotary evaporation of ethanol to obtain concentrate;

[0069] (5) Add the original ethanol amount of 1,3-butanediol to the concentrate to mix evenly, spread a 0.8 μm filter plate in a Buchner funnel for vacuum filtration, and collect the filtrate.

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Abstract

The invention discloses an externally used traditional Chinese medicine composition capable of avoiding allergy and relieving itching. The externally used traditional Chinese medicine composition is prepared from, by weight, 40 to 70 parts of raspberry, 20 to 40 parts of fructus ligustrum lucidum, 10 to 40 parts of haematococcus pluvialis, 30 to 50 parts of frutas galangae, and 10 to 20 parts of oriental cherry flower. It is confirmed by experiments that the externally used traditional Chinese medicine composition possesses extremely excellent inhibition effects on hyaluronidase, so that the externally used traditional Chinese medicine composition possesses excellent allergy prevention effect. The externally used traditional Chinese medicine composition is also capable of relieving itching preferably. Skin care preparations prepared from the externally used traditional Chinese medicine composition are capable of avoiding generation of bloodshot skin preferably. Raw materials are easily available; a preparation method is simple, green, and safe; the externally used traditional Chinese medicine composition can be accepted by allergy sufferers; and application prospect and market prospect are promising.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for external use, in particular to a traditional Chinese medicine composition for external use with antiallergic and antipruritic effects and a traditional Chinese medicine preparation prepared from the skin care composition. Background technique [0002] Changes in the environment affect people's basic necessities of life and human health. There are many factors that affect skin health in the external environment we live in, such as ultraviolet rays, electromagnetic radiation, smog, acid rain, and environmental chemicals that we are familiar with. Hazardous factors can cause many skin problems, the most common being dry skin, allergies, itching and so on. In addition, with the increase of age, the skin also ages, the content of natural moisturizing factors in the stratum corneum decreases, and the lipid level decreases, which reduces the ability of the skin to retain water, causing t...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P17/00A61P17/04A61P37/08A61K8/97A61Q19/00
Inventor 孟宏郑立波
Owner 北京国济众芳中医药研究所
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