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Externally used traditional Chinese medicine composition and preparation which are capable of avoiding allergy and relieving itching, and preparation method thereof

A technology of composition and skin care composition, which is applied in the direction of medical preparations containing active ingredients, drug combinations, skin care preparations, etc., to achieve the effects of easy acceptance, strong inhibitory effect, and simple preparation method

Active Publication Date: 2016-11-30
北京国济众芳中医药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In addition, there are many users whose facial skin has weak stratum corneum, which makes the capillaries easier to contact and perceive the changes in the external environment, resulting in facial red bloodshot symptoms caused by the expansion of capillaries. Such users should be more cautious when choosing skin care products

Method used

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  • Externally used traditional Chinese medicine composition and preparation which are capable of avoiding allergy and relieving itching, and preparation method thereof
  • Externally used traditional Chinese medicine composition and preparation which are capable of avoiding allergy and relieving itching, and preparation method thereof
  • Externally used traditional Chinese medicine composition and preparation which are capable of avoiding allergy and relieving itching, and preparation method thereof

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Effect test

Embodiment 1

[0049] The preparation of embodiment 1 Chinese medicine composition of the present invention

[0050] (1) Take the bulk drug according to the following ratio, pulverize it to 60 mesh, and mix well;

[0051] 65g raspberry, 35g privet fruit, 40g Haematococcus pluvialis, 50g red cardamom, 20g cherry blossom.

[0052] (2) Extract with 95% ethanol by volume, the g / mL mass volume ratio of crude drug and ethanol is 1:15, heat and stir at 70°C for 1 hour to obtain the extract;

[0053] (3) cooling the extract obtained in step (2) to room temperature, and filtering through 120 mesh to obtain the filtrate;

[0054] (4) concentrating the filtrate with rotary evaporating ethanol to a crude drug concentration of 0.5 g / mL to obtain a concentrate;

[0055] (5) Add the original amount of ethanol and 1,3-butanediol to the concentrate to mix evenly, spread a 1.2 μm filter plate in a Buchner funnel for vacuum filtration, and collect the filtrate to obtain the product.

Embodiment 2

[0056] The preparation of embodiment 2 Chinese medicine composition of the present invention

[0057] (1) Take the bulk drug according to the following ratio, pulverize it to 70 mesh, and mix it;

[0058] 40g raspberry, 20g privet fruit, 30g Haematococcus pluvialis, 45g red cardamom, 15g cherry blossom.

[0059](2) Extract with 70% ethanol by volume, the g / mL mass volume ratio of crude drug and ethanol is 1:10, heat and stir at 60°C for 1.5 hours to obtain the extract;

[0060] (3) cooling the extract obtained in step (2) to room temperature, and filtering through 100 mesh to obtain the filtrate;

[0061] (4) concentrating the filtrate to a crude drug concentration of 0.3 g / mL by rotary evaporating ethanol to obtain a concentrate;

[0062] (5) The 1,3-butanediol in the original amount of ethanol is added to the concentrate to mix evenly, spread a 1.5 μm filter plate in a Buchner funnel for vacuum filtration, and collect the filtrate to obtain the product.

Embodiment 3

[0063] The preparation of embodiment 3 Chinese medicine composition of the present invention

[0064] (1) Take the bulk drug according to the following ratio, pulverize it to 80 mesh, and mix well;

[0065] 70g raspberry, 40g privet fruit, 10g Haematococcus pluvialis, 30g red cardamom, 10g cherry blossom.

[0066] (2) extract with 60% ethanol by volume percentage, the g / mL mass-volume ratio of crude drug and ethanol is 1:20, heat and stir at 50°C for 2 hours to obtain the extract;

[0067] (3) cooling the extract obtained in step (2) to room temperature, and filtering through 80 mesh to obtain the filtrate;

[0068] (4) concentrating the filtrate with rotary evaporation ethanol to a crude drug concentration of 0.2 g / mL to obtain a concentrate;

[0069] (5) Add the original amount of ethanol and 1,3-butanediol to the concentrate to mix evenly, spread a 0.8 μm filter plate in a Buchner funnel for vacuum filtration, and collect the filtrate to obtain the product.

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Abstract

The invention discloses an externally used traditional Chinese medicine composition capable of avoiding allergy and relieving itching. The externally used traditional Chinese medicine composition is prepared from, by weight, 40 to 70 parts of raspberry, 20 to 40 parts of fructus ligustrum lucidum, 10 to 40 parts of haematococcus pluvialis, 30 to 50 parts of frutas galangae, and 10 to 20 parts of oriental cherry flower. It is confirmed by experiments that the externally used traditional Chinese medicine composition possesses extremely excellent inhibition effects on hyaluronidase, so that the externally used traditional Chinese medicine composition possesses excellent allergy prevention effect. The externally used traditional Chinese medicine composition is also capable of relieving itching preferably. Skin care preparations prepared from the externally used traditional Chinese medicine composition are capable of avoiding generation of bloodshot skin preferably. Raw materials are easily available; a preparation method is simple, green, and safe; the externally used traditional Chinese medicine composition can be accepted by allergy sufferers; and application prospect and market prospect are promising.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for external use, in particular to a traditional Chinese medicine composition for external use with antiallergic and antipruritic effects and a traditional Chinese medicine preparation prepared from the skin care composition. Background technique [0002] Changes in the environment affect people's basic necessities of life and human health. There are many factors that affect skin health in the external environment we live in, such as ultraviolet rays, electromagnetic radiation, smog, acid rain, and environmental chemicals that we are familiar with. Hazardous factors can cause many skin problems, the most common being dry skin, allergies, itching and so on. In addition, with the increase of age, the skin also ages, the content of natural moisturizing factors in the stratum corneum decreases, and the lipid level decreases, which reduces the ability of the skin to retain water, causing t...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P17/00A61P17/04A61P37/08A61K8/97A61Q19/00
Inventor 孟宏郑立波
Owner 北京国济众芳中医药研究所
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