The invention discloses a multifunctional anti-aging face application agent composition and a use method thereof, and belongs to the technical field of cosmetics and medicines. According to the present invention, according to the matching rule of the main material, the auxiliary material, the adjuvant and the guide material, the components are divided into the antioxidant combination, the elastic and collagen improving agent combination, the Maillard reaction inhibitor combination and the permeation promoting and absorption helping combination, wherein the components of each combination can be combined according to the matching rule of the main material, the auxiliary material, the adjuvant and the guide material; and the multifunctional anti-aging face application agent composition has effects of skin aging delaying, lasting moisturizing, skin elasticity restoration and skin whitening, can well remove wrinkles, under-eye puffiness, freckles, butterfly-shaped spots, chloasma, pregnancy spots and seborrheic keratosis, and further has effects of allergy prevention, inflammation elimination, pain relieving, and wound curing.