A bone repair system for large-stage bone defects

Abstract

The invention provides a bone repair system for large-stage bone defect. The bone repair system comprises a supporting frame and a bone repair material, wherein grids are arranged on the supporting frame; convex bodies are arranged at the outer side of the supporting frame; screw holes are formed in the convex bodies; screws are movably connected to the interiors of the screw holes; the supporting frame is made from a high molecular polymer material or a metal material; the supporting frame is embedded in the bone repair material; and the bone repair material mainly comprise ingredients of collagen, calcium salt and growth factors. By combining the bearing and supporting effects of the supporting frame with the effect of the bone repair material of promoting bone regeneration, bony union of the large-stage bone defect is achieved; and the supporting frame, the convex bodies and the screws are made from a compound of the polylactide copolymer or blend high molecular material and magnesium salt or the metal material of magnesium or magnesium-based alloy, and the materials, after existing in a human body, for a certain duration, can be automatically degraded by the human body and can automatically disappear, so that adverse reactions, and even the risk of infection, caused by long-time existence in the human body are avoided.

Description

technical field [0001] The invention belongs to the field of bone defect repair, in particular to a bone repair system for large-stage bone defect. Background technique [0002] The repair and functional reconstruction of large bone defects caused by congenital bone diseases, trauma, infection or tumor bone resection has always been a difficult problem and research hotspot in the field of orthopedics. Although the traditional autologous bone transplantation has good osteogenesis effect, it has less bone resources, it is difficult to repair a large area of ​​bone defect, and the operation is complicated. , but there are certain limitations. For example, due to the advantages of good biocompatibility, non-toxicity and high strength, the titanium alloy mesh plate is widely used in the clinical application of skull repair, but because titanium alloy is in the human body It cannot be degraded, and patients often have a serious sense of insecurity, especially for patients with la...

AI Technical Summary

Problems solved by technology

Although the traditional autologous bone transplantation has good osteogenesis effect, it has less bone resources, it is difficult to repair a large area of ​​bone defect, and the operation is complicated. , but there are certain limitations. For example, due to the advantages of good biocompatibility, non-toxicity and high strength, the titanium alloy mesh plate is widely used in the clinical application of skull repair, but because titanium alloy is in the human body It cannot be degraded, and patients often have a serious sense of insecurity, especially for patients with large-scale bone defects. The oppressive feeling of large-area titanium alloys will cause headaches, dizziness, fear of vibration, and rejection of titanium alloys. and other syndromes, too long time may cause infection and other problems; and for children's skull repair process, because the children's skull is in the development stage, the skull will continue to grow and change. Symmetry, impact on children's brain development

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