A sebum-promoting agent for improving hair
An accelerator, sebum technology, used in hair care, cosmetic preparations, cosmetics, etc.
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Embodiment 1
[0065] Sample shampoo and conditioner formulations suitable for use in the present invention are shown in Tables 1 and 2.
[0066] Table 1
[0067] Ingredient weight % Shampoo 1 Shampoo 2 Shampoo 3 Sodium Laureth Sulfate 16 14 14 Cocamidopropyl Betaine 2 1.6 1.6 zinc pyrithione 0.25 1.0 0.25 Zinc sulfate --- 0.1 0.1 zinc carbonate 0.25 --- --- Silicone 3.0 2.0 2.0 Climbazole --- 0.5 --- Acrylic Polymer (Carbomer) --- 0.6 0.6 Ethylene Glycol Distearate (EGDS) 1.5 --- Guar Gum Hydroxypropyltrimonium Chloride 0.4 0.2 0.2 Salt, Preservatives and Spices 1.0 1.5 1.5 water to 100 to 100 to 100
[0068] Table 2
[0069]
[0070]
Embodiment 2
[0072] This example demonstrates the effect of applying a shampoo and conditioner comprising zinc pyrithione (ZnPTO) on sebum levels of a dry scalp.
[0073] A clinical study was performed to compare the 0.25% by weight ZnPTO shampoo and 0.25% by weight ZnPTO conditioner system with a commercially available cosmetic shampoo and conditioner system (without sebum booster) causing temporary ( casual) the ability of the scalp to increase sebum levels.
[0074] A half-head, double-blind, randomized design was used. A one-week run-in period at home using a standard (ie, sebum booster-free) shampoo was followed by a half-head salon treatment with 3 washes per week for several weeks. Two treatment systems were randomly assigned to the left and right sides of each head.
[0075]A total of 125 female subjects, aged 18 to 60 and of various races, participated in the trial. All participants had visually dry scalp areas, but none had other scalp disorders. Using as reported in "Assessi...
Embodiment 3
[0081] This example demonstrates the effect of sebum levels on hair smoothness.
[0082] The tresses were treated with model sebum having the composition given in Table 3.
[0083] table 3
[0084]
[0085]
[0086] The amount of model sebum applied to the tresses was calculated using the data from the study in Example 2. This calculation involves assumptions including the following: The sebum meter measures 40% of the total skin surface lipids and the hair density on the scalp is 272.97 hairs / cm 2 And 80% of the sebum on the scalp is transferred to the hair. Using these assumptions and the average number of hairs in a long hair tress, it was determined that 0.705 μl model sebum / 2.5 g hair tress and 0.987 μl model sebum / hair tress were required to simulate a condition with a baseline (25 μg / cm 2 ) and treated (35μg / cm 2 ) hair of subjects with scalp sebum levels.
[0087] The model sebum was applied to the tresses at the root and spread out along the tresses by comb...
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