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4 results about "Climbazole" patented technology

Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff and eczema. Climbazole has shown a high in vitro and in vivo efficacy against Pityrosporum ovale that appears to play an important role in the pathogenesis of dandruff. Its chemical structure and properties are similar to other fungicides such as ketoconazole and miconazole.

Bactericidal and preservative composition

The invention relates to a composition for antibiosis, sterilization and preservation and a product containing the same, and the composition is used for protecting the quality of products in various industrial fields from being damaged by microorganisms. Comprising a family care product group such as a clothes cleaning agent, a dish cleaning agent and a living space cleaning agent, a personal care product group such as a shampoo, a shower gel, a wet tissue and a cleaning product, and a cosmetic product group such as a face cream and an emulsion. The composition for antibiosis and preservation of the present invention comprises a compound represented by chemical formula 1, a compound represented by chemical formula 2, a compound represented by chemical formula 3 or a compound represented by chemical formula 4, so that the problems of harm to human bodies, skin irritation and the like can be solved, and at the same time, the antibacterial ability can be improved. Furthermore, the hair care cosmetic composition for preventing dandruff or the antifungal composition of the present invention, comprising the compound represented by chemical formula 1, has an effect of controlling dandruff fungi, and has a synergistic effect when the compound represented by chemical formula 1 is used together with an expensive dandruff fungus therapeutic agent such as piroctone olamine salt, zinc pyrithione or clomidazole. Moreover, the antiviral composition comprising the compound represented by chemical formula 1 according to the present invention can effectively control microorganisms such as viruses, and thus can be used as an eco-friendly epidemic prevention composition for controlling viruses.
Owner:BJ BIOCHEMICAL CO LTD

Method for promoting anaerobic fermentation of excess sludge to produce acid by climbazole

The invention discloses a method for promoting anaerobic fermentation of excess sludge to produce acid by climbazole, aiming at the technical bottlenecks that the resource recycling of the excess activated sludge is not thorough, the sludge yield is continuously increased, the anaerobic fermentation efficiency of the sludge is low and the yield of volatile fatty acid is insufficient at present. According to the method, environmental pollutant climbazole is creatively added into a sludge anaerobic fermentation system, and acid production enhancement is realized by promoting dissolution of organic matters in sludge and regulating and controlling the metabolic process of microorganisms. The method comprises the following steps: (1) naturally settling the taken residual activated sludge for 24 hours to serve as a fermentation substrate; and (2) fully mixing different doses of climbazole with the fermented sludge obtained after natural sedimentation, and carrying out anaerobic fermentation to generate volatile fatty acid. The existence of climbazole promotes the dissolution of organic matters in the sludge, and provides more substrates for acid production. The method is easy and convenient to operate, a large amount of volatile fatty acid can be generated, recycling and reduction of the sludge are achieved, and guidance is provided for treatment of the sludge containing climbazole.
Owner:TAIYUAN UNIVERSITY OF TECHNOLOGY

Preparation method of high-purity climbazole

The invention discloses a preparation method of high-purity climbazole, and relates to the technical field of synthetic chemistry. The preparation method of the climbazole comprises the following steps: reacting pinacolone with chlorine to obtain chloropinacolone, reacting the chloropinacolone with parachlorophenol to obtain ether ketone, chlorinating the ether ketone with a chlorinating agent to obtain chlorinated ether ketone, reacting the chlorinated ether ketone with imidazole to obtain a crude climbazole product, and refining the crude climbazole product with activated carbon, filtering, crystallizing, centrifuging and drying to obtain the climbazole. The chlorination reagent used in the ether ketone chlorination stage and a proper adding mode improve the reaction selectivity, SO2 by-products which cause pollution to the environment are not generated, and the environmental protection property is high; an additional catalyst is not used in the reaction process of chloro-ether-ketone and imidazole, and recyclable activated carbon is used in the purification of a climbazole crude product, so that the preparation cost is reduced; the climbazole prepared by the method has high yield and high purity, and is suitable for industrial production.
Owner:HEILONGJIANG BANGPU BIOTECHNOLOGY CO LTD

Disinfectant and preservative compositions

PendingUS20260182568A1AntifungalHome use
Disclosed are antibacterial, sterilizing and preservative compositions that protect products in various industrial fields, including home care products such as clothing detergents, dish detergents, and home cleaners, personal care products such as shampoos, body cleansers, wet tissues, and cleansers, and cosmetic products such as creams and emulsions, and products containing the same. The compositions contain a compound of Formula 1, optionally in combination with other compounds. Moreover, the anti-dandruff hair care cosmetic composition or antifungal composition containing the compound represented by Formula 1 is effective in controlling dandruff bacteria. When combined with piroctone olamine, zinc pyrithione, or climbazole, the composition has synergistic effects. In addition, the antiviral composition containing the compound represented by Formula 1 effectively controls microorganisms such as viruses and can be used as an eco-friendly quarantine composition.
Owner:BJBIOCHEM CO LTD