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Traditional Chinese medicine effective fraction compound preparation for treating pruritus vulvae and vaginal itching, and preparation method thereof

A technology for effective site and vaginal itching, which can be used in medical preparations containing active ingredients, pharmaceutical formulations, active ingredients of hydroxyl compounds, etc., and can solve problems such as pseudo-aldosterone-like symptoms

Inactive Publication Date: 2017-03-01
FOSHAN SOIN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, Ganlin lotion uses licorice as the main drug, which is directly used after simple extraction. Although the market response is good, the glycyrrhizic acid in it has a corticosteroid-like effect, and long-term use can produce pseudo-aldosterone-like symptoms.

Method used

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  • Traditional Chinese medicine effective fraction compound preparation for treating pruritus vulvae and vaginal itching, and preparation method thereof
  • Traditional Chinese medicine effective fraction compound preparation for treating pruritus vulvae and vaginal itching, and preparation method thereof
  • Traditional Chinese medicine effective fraction compound preparation for treating pruritus vulvae and vaginal itching, and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0041] A compound preparation of effective parts of traditional Chinese medicines for treating vulva and vaginal itching, wherein the components of effective parts of traditional Chinese medicines include:

[0042]

[0043]

[0044] The rest are additives and purified water. The auxiliary agent includes organic solvent, polysorbate solubilizer, polyhydric alcohol moisturizing agent and organic acid.

[0045] The total flavonoids of licorice described in the present invention is the extract of licorice, and the total flavonoids of licorice used are calculated as liquiritin (UV method), and its mass content is not less than 50%, preferably not less than 60%, more preferably not less than 70% . Licorice is a leguminous plant, which has the effect of clearing away heat and detoxifying, among which flavonoids and glycyrrhizic acid are the main active ingredients. Glycyrrhizic acid also has anti-inflammatory and anti-allergic effects, but long-term use will cause corticoster...

Embodiment 2

[0055] A compound preparation of effective parts of traditional Chinese medicines for treating vulva and vaginal itching, wherein the components of effective parts of traditional Chinese medicines include:

[0056]

[0057] The rest are auxiliary agents and purified water, and the auxiliary agents include organic solvents, polysorbate solubilizers, polyhydric alcohol moisturizing agents and gel matrix.

[0058] The preparation method of the gel of the Chinese medicine effective part compound preparation for treating vulva and vaginal itching of the present invention is as follows:

[0059] Step S1: Dissolving total flavonoids of licorice, total coumarin and borneol in polyethylene glycol 400 organic solvent, adding polysorbate 60 solubilizer, and stirring evenly to obtain standby medicinal solution A.

[0060] Step S2: adding the total glycosides of gardenia leaves and matrine into the purified water, and stirring evenly to obtain the standby medicinal solution B. In this ...

Embodiment 3

[0063] A compound preparation of effective parts of traditional Chinese medicines for treating vulva and vaginal itching, wherein the components of effective parts of traditional Chinese medicines include:

[0064]

[0065] The rest are additives and purified water. The adjuvant is cream or ointment base.

[0066] The preparation method of the cream or ointment of the compound preparation of the effective part of the traditional Chinese medicine for treating vulva and vaginal itching is as follows:

[0067] Step S1: crush or grind the total flavonoids of licorice, total coumarin and borneol into medicinal powder.

[0068] Step S2: adding matrine and total glycosides of gardenia leaves into purified water, and stirring evenly to obtain a spare liquid medicine. In this step, propylene glycol may also be added, and stirring evenly.

[0069] Step S3: Add the medicinal powder and medicinal solution to the cream or ointment base, and stir evenly.

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Abstract

The invention provides a traditional Chinese medicine effective fraction compound preparation for treating pruritus vulvae and vaginal itching, wherein the effective fraction components comprise, by weight, 15-50 parts of licorice root total flavonoids, 10-50 parts of gardenia jasminoides ellis leaf total glycosides, 10-30 parts of cortex fraxini total coumarin, 10-30 parts of matrine, 0.2-10 parts of borneol, and the balance of an auxiliary agent and purified water, and the traditional Chinese medicine effective fraction compound preparation has characteristics of high efficacy and less adverse reaction. The invention further provides a preparation method for different dosage forms of the preparation, wherein the production is simple and easy to promote, and the obtained preparation product has excellent and table performances.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a compound preparation of effective parts of traditional Chinese medicine for treating vulva and vaginal itching and a preparation method thereof. Background technique [0002] There are many reasons for genital itching, the most common local factors causing the disease are: 1. External stimulation: Sometimes contraceptives can also cause itching, and underwear is too tight, and the stimulation of underwear friction can also cause itching. Due to not paying attention to vulva hygiene, vaginal secretion irritants, vulvar secretions, sweat and other stimuli, vulva and vaginal drug allergies, and frequent washing of vulva with soap can all lead to vulva itching. Genital itching is often accompanied by anal itching. ② Local diseases of the vulva: Local diseases of the vulva include gonorrhea, non-gonococcal urethritis, fungal or trichomonal vaginitis, scabies...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61K9/06A61K9/02A61P15/00A61P17/04A61K31/045A61K31/4375
Inventor 王建芳
Owner FOSHAN SOIN PHARMA CO LTD
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