Schiff base compound based on tetraphenylethylene and mandelonitrile as well as preparation method and application of Schiff base compound

A technology of tetraphenylethylene and tetraphenylethylene, which is applied in the field of analysis and detection, and can solve the problems of low fluorescence efficiency and inability to realize the application of red fluorescent probes.
CN106478458AActive Publication Date: 2017-03-08HKUST SHENZHEN RES INST

Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
HKUST SHENZHEN RES INST
Publication Date
2017-03-08

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Abstract

The invention relates to a Schiff base compound based on tetraphenylethylene and mandelonitrile as well as a preparation method and an application of the Schiff base compound. Compared with common Salen type mandelonitrile fluorescent probe structures, probe structures in the type have excellent red fluorescent behaviors and excellent solid state (state of aggregation) efficiency, realize selective recognition and imaging of specific structures in cells, have better responsiveness to anions, cations and pH values, thereby having extremely broad application prospect in the fields of biology, medical treatment, health and monitoring.
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Description

technical field

[0001] The invention relates to the technical field of analysis and detection, more specifically, to a Schiff base compound based on tetraphenylethylene and maleonitrile, a preparation method and application thereof. Background technique

[0002] With the rapid development of the national economy and the continuous improvement of people's living standards, real-time monitoring of personal health, disease prevention and treatment have gradually become people's livelihood issues that people pay more attention to. Compared with the delay of traditional in vitro chemical testing and the harmfulness of online radiation detection, fluorescence online imaging technology has gradually entered people's field of vision with its advantages of high efficiency, greenness and strong real-time performance, and has been widely used in cellular immunology, microbiology, etc. Science, molecular biology, genetics, neurobiology, pathology, oncology, clinical laboratory science, ...

Claims

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