Phellinus igniarius and ganoderma lucidum capsules and preparation method thereof
A technology of Phellinus linteus and Ganoderma lucidum capsules is applied in the field of high-content Phellinus linteus Ganoderma lucidum capsules and the field of preparation thereof to achieve the effects of reducing dosage, improving efficacy and improving bioavailability
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Embodiment 1
[0044] Preparation of Phellinus Phellinus Extract:
[0045]Take Phellinus linteus, pulverize it, add 1:1 ethyl acetate and ethanol, heat under reflux for 40 minutes, extract 3 times, and combine the filtrates to obtain Extract I; the medicinal residues are added with 70% ethanol, heated under reflux for 40 minutes, extracted twice, and the filtrate is Merge extract II, concentrate extract II into extract, dissolve extract with 50% methanol, use ODS-C18 column to separate it, first use 8% methanol as mobile phase, get eluent I, then replace 60% methanol was used as the mobile phase to obtain eluent II, which was concentrated and dried to obtain the sample; the sample obtained by continued separation by preparative liquid chromatography: separation conditions of preparative chromatography: the chromatographic column was a semi-preparative column Lichrospher-C18; 10.0mmX250mm, 5μm , the mobile phase is A is water and B is acetonitrile, and the gradient elution procedure is as fol...
Embodiment 2
[0060] The preparation method is the same as in Example 1
[0061] It's just that the dosage ratio of Phellinus linteus extract, Ganoderma lucidum extract, Ganoderma lucidum spore oil and beeswax is 1:1:2:1.
Embodiment 3
[0063] The preparation method is the same as in Example 1
[0064] Only the dosage ratio of Phellinus linteus extract, Ganoderma lucidum extract, Ganoderma lucidum spore oil and beeswax is 2:1:3:1.
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