Cystitis glandularis and bladder cancer diagnosis differential marker, diagnostic reagent or kit
A diagnostic reagent and technology for cystitis, applied in the field of biomarkers, can solve problems such as increasing the examiner's physical and psychological pain, inappropriate bladder inspection, and inappropriate bladder capacity inspection.
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Embodiment 1
[0031] Example 1: Diagnosis and distinction between cystitis glandularis and bladder cancer based on circulating microRNA in peripheral blood
[0032] Part 1: Screening Phase
[0033] 1. Experimental materials and experimental methods
[0034] 1. Plasma samples: 23 cases of cystitis glandular research subjects, aged 45 to 55 years, with an average age of 51.3 years, 12 males and 11 females, 6 cases of chronic inflammatory type (3M / 3F), filtration 5 cases of blister edema type (3M / 2F), 5 cases of papilloma type (2M / 3F), and 7 cases of intestinal adenomatous type (4M / 3F); 21 cases of bladder cancer group, aged 43-54 years, The average age was 50.1 years, 12 males and 9 females, specifically bladder urothelial carcinoma (12M / 9F). All cases were newly diagnosed and had no history of drug treatment. There was no significant difference in the age of the subjects in each group, and all patients had normal heart, lung, liver, kidney and hematopoietic functions. The peripheral ven...
Embodiment 2
[0054] Example 2: Diagnosis and distinction between cystitis glandularis and bladder cancer based on plasma small molecule metabolites
[0055] Part 1: Screening Phase
[0056] 1. Experimental materials and experimental methods
[0057] 1. Plasma samples: 23 cases of cystitis glandular research subjects, aged 45 to 55 years, with an average age of 51.3 years, 12 males and 11 females, 6 cases of chronic inflammatory type (3M / 3F), filtration 5 cases of blister edema type (3M / 2F), 5 cases of papilloma type (2M / 3F), and 7 cases of intestinal adenomatous type (4M / 3F); 21 cases of bladder cancer group, aged 43-54 years, The average age was 50.1 years, 12 males and 9 females, specifically bladder urothelial carcinoma (12M / 9F). All cases were newly diagnosed and had no history of drug treatment. There was no significant difference in the age of the subjects in each group, and all patients had normal heart, lung, liver, kidney and hematopoietic functions. The peripheral venous bl...
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