A kind of solid pharmaceutical composition containing sarcogrelate hydrochloride
A technology of sarcogrelate hydrochloride and its composition, which is applied in the field of sarcogrelate hydrochloride oral solid composition, and can solve the problems of poor selectivity and the like
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Embodiment 50
[0104] Example Preparation of film-coated tablets of 50mg and 100mg sargresil hydrochloride
[0105] prescription:
[0106]
[0107] The above formulation is prepared into film-coated tablets through the following steps:
[0108] a. Weigh the prescribed amount of sagogrelate hydrochloride and citric acid and crush them through a 100 mesh sieve, lactose and starch through a 100 mesh sieve, hydroxypropyl cellulose and hypromellose through 80 mesh, and magnesium stearate through 60 mesh. Sieve, spare;
[0109] b. Weigh the prescribed amount of hypromellose and prepare a 2.5% solution with purified water as a binder for use;
[0110] c. Take the prescription amount of citric acid, hydroxypropyl cellulose and an appropriate amount of lactose monohydrate, double and mix, and mix with the prescription amount of sargrelate hydrochloride, starch, and the remaining lactose monohydrate, and set aside;
[0111] e. Add adhesive to make soft material. Granulate with 24 mesh sieve, dry at 60±5℃, loss...
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