Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Microneedle containing retinol or retinol derivative

A technology of retinol and derivatives, which is applied in the direction of microneedles, medical devices, medical preparations of non-active ingredients, etc., can solve the problems of small effect, skin irritation, and protein synthesis, so as to reduce skin irritation and ensure stability sexual effect

Inactive Publication Date: 2017-05-10
LG HOUSEHOLD & HEALTH CARE LTD
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this retinol derivative cannot penetrate deeply into the skin to synthesize protein like retinol, so although the stability is high, the effect is relatively small
[0007] In addition, when retinol is absorbed into the skin, it often causes problems that induce skin irritation such as erythema

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Microneedle containing retinol or retinol derivative
  • Microneedle containing retinol or retinol derivative
  • Microneedle containing retinol or retinol derivative

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0036] Hereinafter, in order to help the understanding of the present invention, a detailed description is given with examples. However, the embodiments of the present invention can be modified into various other forms, and the scope of the present invention should not be interpreted as being limited to the following embodiments. The embodiments of the present invention are provided in order to fully explain the present invention to people with average knowledge in the field.

[0037]

[0038] 10g of polylactic acid (PLA) and 10g of diblock copolymer (MPEG-PCL: mono-methoxy poly ethylene glycol-Poly carprolactone) After dissolving in 100 g of methylene chloride (Methylene Chloride), 5 g of retinol 50C (BASF, 50% retinol) was mixed to produce a polymer-retinol solution. 2.5 g of polyvinyl alcohol (PVA: Poly vinyl alcohol) was dissolved in 500 mL of purified water to prepare a PVA aqueous solution. 500 mL of the PVA aqueous solution was stirred at 700 rpm, and a polymer-retinol s...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
Login to View More

Abstract

The present invention relates to a system for administering retinol to the skin, capable of ensuring the stability of retinol, reducing skin irritation caused by retinol and continuously exhibiting effects, and is characterized by a microneedle into which microparticles containing retinol or a retinol derivative are added. In addition, the present invention provides a preparation method for a system for administering retinol, capable of reducing skin irritation, exhibiting retinol effects for a long time and ensuring the stability of retinol which is very unstable with respect to light, moisture, temperature and the like. Additionally, the present invention provides a method for administering retinol to the skin, characterized by using the microneedle.

Description

Technical field [0001] The present invention relates to a retinol transdermal drug delivery system that can reduce skin erythema and other side effects, improve the stability of retinol, and show long-term effects, and in particular to a microneedle containing retinol (Microneedle ) And its manufacturing method. [0002] This application claims priority based on Korean Patent Application No. 10-2014-0094220 filed on July 24, 2014, and incorporates all the contents disclosed in the specification and drawings of the above-mentioned application into this application. Background technique [0003] As a kind of vitamin A, retinol plays an important role in maintaining the original functions of the epidermal cells of the skin. Specifically, retinol is believed to have the following effects: the DNA present in the nucleus of skin cells expresses RNA to promote cell differentiation, promote the biosynthesis of elastin, etc., to reduce wrinkles and increase skin elasticity. The elastin is...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00A61K9/16A61K31/07A61K47/30
CPCA61K47/10A61K9/1641A61K9/1647A61K31/07A61K9/0021A61K47/26A61K47/36A61K47/38A61M37/0015A61M2037/0023A61M2037/0053A61M2037/0061A61P17/00A61P43/00A61K9/16
Inventor 沈愚先金东灿黄英暋李鲜和姜来圭朴宣圭李天九
Owner LG HOUSEHOLD & HEALTH CARE LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com