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A kind of black wolfberry polysaccharide chewable tablet

A technology of black wolfberry and chewable tablets, which is applied in the fields of metabolic diseases, medicines, anti-toxins, etc., can solve the problem of lack of black wolfberry polysaccharides, etc., and achieve the effects of rapid drug dissolution, convenient administration, and fast absorption

Active Publication Date: 2020-01-17
河北康平健康产业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, most of the research on black wolfberry polysaccharides focuses on the extraction method / process research, pharmacological activity research, etc., and there is a lack of functional health food involving black wolfberry polysaccharides as a single active ingredient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A chewable black wolfberry polysaccharide tablet, the main components of which include: 45g of black wolfberry polysaccharide, 250g of mannitol, 8g of citric acid syrup, 12g of hydroxypropyl cellulose, 24g of povidone K30, and 5g of micronized silica gel; the preparation method comprises the following steps :

[0025] (1) Preparation of black wolfberry polysaccharide:

[0026] (a) select high-quality black wolfberry, wash with clean water, dry, and pulverize into coarse powder for subsequent use;

[0027] (b) extracting the black wolfberry coarse powder obtained in step (a) through hot water for 3 times, each time for 2 hours, merging the obtained extracts, filtering, and concentrating to 1 / 2 of the original volume;

[0028] (c) adding 2 times the volume of petroleum ether to the concentrated solution obtained in step (b) for extraction, extracting 4 times, discarding the petroleum ether extraction layer, and merging the extracted water layer for subsequent use;

[00...

Embodiment 2

[0036] A black wolfberry polysaccharide chewable tablet, the main components include: black wolfberry polysaccharide 50g, mannitol 270g, citric acid syrup 8g, hydroxypropyl cellulose 10g, povidone K30 25g, micronized silica gel 6g; its preparation method comprises the following steps :

[0037] (1) Preparation of black wolfberry polysaccharide:

[0038] (a) select high-quality black wolfberry, wash with clean water, dry, and pulverize into coarse powder for subsequent use;

[0039] (b) extracting the black wolfberry coarse powder obtained in step (a) twice with hot water, each time for 2.5 hours, merging the obtained extracts, filtering, and concentrating to 1 / 2 of the original volume;

[0040] (c) adding 1.5 times the volume of petroleum ether to the concentrated solution obtained in step (b) for extraction, extracting 3 times, discarding the petroleum ether extraction layer, and merging the extracted water layer for subsequent use;

[0041] (d) adding an appropriate amount...

Embodiment 3

[0048] A kind of black wolfberry polysaccharide chewable tablet, main component comprises: black wolfberry polysaccharide 60g, mannitol 300g, citric acid syrup 9g, hydroxypropyl cellulose 15g, povidone K30 30g, micropowder silica gel 6g and its preparation method comprises the following steps:

[0049] (1) Preparation of black wolfberry polysaccharide:

[0050] (a) select high-quality black wolfberry, wash with clean water, dry, and pulverize into coarse powder for subsequent use;

[0051] (b) extracting the black wolfberry coarse powder obtained in step (a) 3 times with hot water, each time for 2.5 hours, merging the obtained extracts, filtering, and concentrating to 1 / 2 of the original volume;

[0052] (c) Add 2 times the volume of petroleum ether to the concentrated solution obtained in step (b) for extraction, extract 3 times, discard the petroleum ether extraction layer, and combine the extracted water layers for subsequent use;

[0053] (d) adding an appropriate amount of...

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PUM

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Abstract

The invention relates to a Lycium ruthenicum polysaccharide chewable tablet which mainly comprises Lycium ruthenicum polysaccharides, mannitol citric acid syrup, hydroxypropyl cellulose, povidone K30 and micropowder silica gel. The Lycium ruthenicum is leached with hot water and extracted with petroleum ether to remove grease and pigments, thereby greatly removing the impurities and maintaining more polysaccharide components; and after alcohol precipitation, gel column chromatography is carried out to perform purification and refinement, so the drug effect is centralized, thereby fully displaying the pharmacological activity of the Lycium ruthenicum polysaccharides. The chewable tablet has the advantages of favorable mouthfeel, short disintegration time, favorable dispersion effect, quick drug leaching, quick absorption, high bioavailability and the like. The chewable tablet is convenient to take, and is especially suitable for children, old people and patients with dysphagia to take.

Description

technical field [0001] The invention relates to a black wolfberry polysaccharide chewable tablet, which belongs to the field of functional foods. Background technique [0002] Black wolfberry, also known as black fruit wolfberry, belongs to the genus Lycium barbarum of the family Solanaceae. Perennial shrub with thorns, spherical berries, purple-black when mature, high photosynthetic efficiency and strong stress resistance, is a unique wild plant in the desert area of ​​Northwest my country that needs to be developed urgently, distributed in Shanxi, Ningxia, Gansu , Qinghai, Xinjiang, Tibet and other regions. Black wolfberry is sweet and juicy, rich in vitamins, organic acids and sugars, and is often eaten raw or squeezed to make beverages. Black wolfberry has certain medical and health care functions. Tibetan medicine uses it to treat heart fever, heart disease, irregular menstruation, menopause and other diseases. [0003] Black wolfberry is rich in protein, fat, sugar, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K31/715A61P39/00A61P3/10A23L33/105A23L33/125A23P10/28C08B37/00
CPCA23V2002/00A61K9/0056A61K9/2054A61K31/715A61K36/815A61K2236/331A61K2236/35A61K2236/39A61K2236/55C08B37/0003C08B37/006A23V2200/14A23V2200/30A23V2250/21
Inventor 贾东升谢晓亮温春秀刘灵娣崔施展李荣乔田伟边建波
Owner 河北康平健康产业有限责任公司
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