Natural medicine composition for treating involutional depression and non-classical depression and use of natural medicine composition

A technology of natural medicine and depression disorder, applied in the direction of drug combination, drug delivery, medical preparations containing active ingredients, etc., can solve the problems of side effects and curative effect, and achieve the effect of rapid drug effect, safe dosage and reasonable compatibility

Inactive Publication Date: 2017-05-24
SHAANXI TIANKUI BIOMEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the defects in the above-mentioned prior art, the object of the present invention is to provide a natural pharmaceutical composition for the treatment of climacteric depression and atypical depressive disorders and its application, the natura

Method used

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  • Natural medicine composition for treating involutional depression and non-classical depression and use of natural medicine composition
  • Natural medicine composition for treating involutional depression and non-classical depression and use of natural medicine composition
  • Natural medicine composition for treating involutional depression and non-classical depression and use of natural medicine composition

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preparation example Construction

[0024] The preparation method of raw material preparation of the present invention can adopt following three kinds:

[0025] 1) The preparation of seabuckthorn fruit oil, common methods are as follows:

[0026] ①Physical pressing and centrifugal separation: Seabuckthorn fruit juice and seabuckthorn fruit puree obtained by pressing (seeding off) ripe fresh seabuckthorn fruits (seeded) with a screw rod. The fruit puree is soaked in warm water at 50-55°C for 2-3 times for 1.5 hours, centrifuged several times, and the oil extraction rate of seabuckthorn fruit oil is 1.6%-2.2% (g / g).

[0027] ②CO2 supercritical extraction: Ripe seabuckthorn fruit (seeded) is dried at constant temperature to obtain dried seabuckthorn fruit puree. Extraction conditions for industrial production: extraction pressure 35MPa, extraction temperature 45°C. The extraction time is 1.5h, and the separation temperature is 45°C. The oil extraction rate can reach 5.0%-5.6% (g / g). Add water at a ratio of 1:1 ...

Embodiment 1

[0035] The natural medicine prescription for the treatment of climacteric and / or climacteric mental depression and atypical depressive disorders is a medicament prepared from raw materials in the following mass percentages: 96.7% (g / kg) seabuckthorn fruit oil, 3.3% ( g / kg) of Panax notoginseng total saponins.

Embodiment 2

[0037] The natural medicine composition prescription for the treatment of climacteric and / or climacteric mental depression and atypical depressive disorders is a medicament prepared from raw materials in the following mass percentages: 84.0% (g / kg) seabuckthorn fruit oil, 16.0% ( g / kg) of Panax notoginseng total saponins.

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Abstract

The invention discloses a natural medicine composition for treating involutional depression and non-classical depression and use of the natural medicine composition, and belongs to the technical field of research of natural medicine formulas in compatibility dosage effect and use of the natural medicine. The composition consists of the components in percentage by mass: 70%-97.5% of hippophae rhamnoides fruit oil and 2.5%-30% of pseudo-ginseng stem and leaf total saponins. The natural medicine composition disclosed by the invention is reasonable in compatibility and safe in dosage, is free from any side effects on human bodies, can solve the problems that a conventional medicine has side effects and poor treatment effects when being used for treating climacterium and involutional depression, and has a significant regulation effect on serum marker indexes, namely adenylate cyclase-cyclic adenosine monophosphate and cyclic guanosine monophosphate, and reproductive hormonesm and target acceptors of various impact factors, such as follicular generation promoting hormones, pitocin, dihydrotestosterone hormones, female hormones, adrenocorticotropin hormones, cytokine interleukin-6, interleukin-8 cytokine and interleukin-2, so as to achieve a treatment effect on treatment of the involutional depression and the non-classical depression diseases.

Description

technical field [0001] The invention belongs to the technical field of research on prescriptions and dose-effect applications of natural medicines, and in particular relates to a prescription of natural medicines for treating climacteric depression and atypical depression and its application. Background technique [0002] Menopausal depression is a class of neurotic disorders due to endocrine disorders, sexual organ function decline (ovarian function decline or aging) that lead to mental excitement and emotional depression, worry and psychophysiological symptoms of depression. Menopausal depression is a syndrome caused by mental anxiety, tension, depression and other factors when the first onset age is menopause (55-60 years old for men, 45-55 years old for women). Common clinical symptoms include anxiety, nervousness and fear, a little startled and overwhelmed, depressed, pessimistic and disappointed, often crying, self-blame, subjective judgment, suspicion of others, or su...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61P15/12A61P25/24A23L1/29
CPCA61K36/185A61K36/258A61P5/10A61P5/08A61P25/24A61K2300/00A61K9/0053A61K9/48A61K36/72
Inventor 魏霞蓁宋兰兰韩少华
Owner SHAANXI TIANKUI BIOMEDICAL TECH
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