Compound preparation for treating acute glomerulitis

A technology of glomerulitis and compound preparations, which is applied in the direction of medical preparations containing active ingredients, drug combinations, organic active ingredients, etc., can solve the problems of large side effects and high costs, and achieve rapid onset, stable action, and non-toxicity side effects

Inactive Publication Date: 2017-05-31
ZHENGZHOU RENHONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the effective treatment of acute glomerulonephritis is mainly thr...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A compound preparation for treating acute glomerulitis, the main raw materials according to weight parts are: 8 parts of harringtonine, 2 parts of vanillin, 7 parts of evodicarpine, 15 parts of cork ketone, 12 parts of narcissin, 4 parts of 7-ethylcamptothecin, 4 parts of menthol, 26 parts of limonin, 7 parts of indigoside, and 2 parts of alisol A-24-acetate.

[0016] A preparation method of a compound preparation for the treatment of acute glomerulitis, the concrete steps are:

[0017] First, in the pharmaceutical-grade clean area, weigh harringtonine, vanillin, evodicarpine, corkine, thiocolchicine, 7-ethylcamptothecin, menthol according to the above measurement ratio. , limonin, indigoside, alisol A-24-acetate, sieve, mechanically mix, add ultrapure water, place in a pharmaceutical mixer, mix for 4min, control RSD≤5%, press after mixing The tablet is dried at low temperature, the temperature is controlled at 4°C, and the compound preparation for treating acute glome...

Embodiment 2

[0019] A compound preparation for treating acute glomerulitis, the main raw materials according to weight parts are: 11 parts of harringtonine, 2 parts of vanillin, 8 parts of evodicarpine, 17 parts of cork, 14 parts of narcissin, 4 parts of 7-ethylcamptothecin, 4 parts of menthol, 26 parts of limonin, 7 parts of indigoside, and 2 parts of alisol A-24-acetate.

[0020] A preparation method of a compound preparation for the treatment of acute glomerulitis, the concrete steps are:

[0021] First, in the pharmaceutical-grade clean area, weigh harringtonine, vanillin, evodicarpine, corkine, thiocolchicine, 7-ethylcamptothecin, menthol according to the above measurement ratio. , limonin, indigoside, alisol A-24-acetate, sieve, mechanically mix, add ultrapure water, place in a pharmaceutical mixer, mix for 4min, control RSD≤5%, press after mixing The tablet is dried at low temperature, the temperature is controlled at 4°C, and the compound preparation for treating acute glomeruliti...

Embodiment 3

[0023] A compound preparation for treating acute glomerulitis, the main raw materials according to weight parts are: 15 parts of harringtonine, 4 parts of vanillin, 9 parts of evodicarpine, 19 parts of cork, 15 parts of narcissin, 5 parts of 7-ethylcamptothecin, 6 parts of menthol, 27 parts of limonin, 10 parts of indigoside, and 3 parts of alisol A-24-acetate.

[0024] A preparation method of a compound preparation for the treatment of acute glomerulitis, the concrete steps are:

[0025] First, in the pharmaceutical-grade clean area, weigh harringtonine, vanillin, evodicarpine, corkine, thiocolchicine, 7-ethylcamptothecin, menthol according to the above measurement ratio. , limonin, indigoside, alisol A-24-acetate, sieve, mechanically mix, add ultrapure water, place in a pharmaceutical mixer, mix for 6min, control RSD≤5%, press after mixing The tablet is dried at low temperature, the temperature is controlled at 6°C, and the compound preparation for treating acute glomerulit...

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PUM

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Abstract

The invention discloses a compound preparation for treating acute glomerulitis. The compound preparation for treating acute glomerulitis is prepared from the following main raw materials in parts by weight: 8-22 parts of harringtonine, 2-6 parts of didymin, 7-11 parts of fructus evodiae, 15-20 parts of friedelin, 12-18 parts of thiocolchicoside, 4-6 parts of 7-ethylcamptothecin, 4-8 parts of menthol, 26-28 parts of limonin, 7-12 parts of sissotrin and 2-4 parts of alisol A-24 acetate. The raw materials are strictly selected according to the known mechanism of the acute glomerulitis, so that the aim of comprehensive rehabilitation is achieved; and the compound preparation has the characteristics of being high in effect taking speed, stable in action, convenient to carry and take and free of toxic or side effect after being taken for a long period of time.

Description

technical field [0001] The invention relates to the field of medicine preparation, in particular to a compound preparation for treating acute glomerulitis. Background technique [0002] Acute glomerulonephritis (acute glomerulonephritis) is often referred to as acute nephritis. Acute nephritis is a disease mainly caused by diffuse glomerular damage on both sides of the kidneys caused by allergic reactions after infection. In a broad sense, it refers to a group of glomerular diseases with different etiologies and pathogenesis, but clinically manifested as acute onset, characterized by hematuria, proteinuria, edema, hypertension and decreased glomerular filtration rate. Often called acute nephritic syndrome. The vast majority of clinical cases belong to acute post-streptococcal glomerulonephritis. The disease can occur at any age and is more common in children. More common in the age of 3 to 8 years old, rare under 2 years old. The male to female ratio is approximately 2:...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61K31/55A61K31/7048A61K31/47A61K31/56A61K31/4745A61K31/045A61K31/585A61P13/12
CPCA61K31/704A61K31/045A61K31/47A61K31/4745A61K31/55A61K31/56A61K31/585A61K31/7048A61K2300/00
Inventor 不公告发明人
Owner ZHENGZHOU RENHONG PHARMA CO LTD
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