A Method of Using Correlation Coefficient to Process Drug Database Data
A correlation coefficient and data processing technology, applied in the field of database management, can solve the problems of model applicability, limited accuracy, high cost, and large investment, and achieve the effects of small limitations, strong openness, and improved practicability
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Embodiment 1
[0062] Example 1: Construction and Application of Tablet Near-infrared Spectral Library
[0063] The first part, the construction of tablet near-infrared spectral library
[0064] Tablets refer to tablet-shaped solid preparations made by mixing and pressing drugs and suitable excipients. It is one of the most widely used varieties in modern pharmaceutical preparations. Tablets for oral use are divided into: tablets, coated tablets , Effervescent Tablets, Chewable Tablets, Dispersible Tablets, Sustained Release Tablets, Controlled Release Tablets, Multilayer Tablets, Orally Disintegrating Tablets. Tablet varieties (m=4) in the existing drug library were sorted out, including sparfloxacin tablets (n=73, spectral collection method: aluminum-plastic or direct contact measurement), clarithromycin sustained-release tablets ( n=54, spectrum collection method: aluminum-plastic insulation) and amoxicillin dispersible tablets (n=65, spectrum collection method: direct contact measuremen...
Embodiment 2
[0080] Example 2: Construction and application of powder injection near-infrared spectral library
[0081] The first part, the construction of powder injection near-infrared spectral library
[0082] Powder injection is a powdery article formed by mixing drugs and reagents, and then sterilized and dried. According to the preparation principle, it can be divided into sterile powder and freeze-dried powder.
[0083] Sort out the types of powder injections in existing medicines (m=6), including ceftriaxone sodium for injection (n=118, spectrum acquisition method: vials), ceftizoxime sodium for injection (n=110, spectrum Collection method: vial vial), cefuroxime sodium for injection (n=32, spectrum collection method: vial vial), cefotaxime sodium for injection (n=29, spectral collection method: vial vial), Cefoperazone Sodium for Injection (n=40 samples, spectrum acquisition method: vial vial), cefepime hydrochloride for injection (n=35 samples, spectral acquisition method: vial ...
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