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A kit for early diagnosis of diabetic nephropathy

A technology for early diagnosis of diabetic nephropathy, applied in instruments, measuring devices, scientific instruments, etc., can solve the problems of high missed diagnosis rate, insufficient specificity and sensitivity, and achieve the effect of easy operation.

Active Publication Date: 2018-11-06
ANHUI HUIBANG BIOLOGICAL ENG
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Problems solved by technology

[0003] At present, the traditional methods for early diagnosis of diabetic nephropathy have deficiencies. The traditional detection methods used at home and abroad to predict diabetes, nephropathy and its development trend are blood creatinine examination, urine microalbumin examination or urine microalbumin to creatinine ratio (ACR) examination. This traditional blood creatinine method for judging kidney disease has a high rate of misdiagnosis; for the diagnostic method of urinary microalbuminuria, in fact, almost all type 1 and most type 2 diabetic patients have microalbuminuria to varying degrees. Renal damage, and many patients have progressive renal damage, but urinary albumin does not increase, so the specificity and sensitivity of this method are not enough

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  • A kit for early diagnosis of diabetic nephropathy
  • A kit for early diagnosis of diabetic nephropathy
  • A kit for early diagnosis of diabetic nephropathy

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Embodiment Construction

[0019] The present invention will be described in detail below with reference to the accompanying drawings and examples.

[0020] The kit for early diagnosis of diabetic nephropathy according to an embodiment of the present invention includes urine microalbumin test strips, haptoglobin test strips and creatinine test strips.

[0021] The inventors have found that haptoglobin is closely related to the decline of renal function in the early stage of diabetes and its progressive deterioration, and can be used as another indicator to monitor the change of renal function in diabetic patients. The invention can increase the detection rate of early diabetic nephropathy to more than 95% by simultaneously detecting the ratio of urine microalbumin to creatinine and haptoglobin, which is of great significance.

[0022] In one embodiment, the urine microalbumin test strip adopts the principle of colloidal gold competition method, see figure 1 , the microalbuminuria test strip comprises a...

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Abstract

The invention discloses a kit applied to early diagnosis of diabetic nephropathy. The kit comprises a urine microalbumin test strip, a haptoglobin test strip and a creatinine test strip. By adopting the kit, the three indexes of urine microalbumin, haptoglobin and creatinine can be detected simultaneously with one sample, and early diabetic nephropathy detection rate is increased to 95 percent or more.

Description

technical field [0001] The invention relates to the field of detection kits, in particular to a kit for early diagnosis of diabetic nephropathy. Background technique [0002] Diabetes is a group of metabolic diseases characterized by hyperglycemia. Hyperglycemia is caused by defective insulin secretion or impaired biological action, or both. The long-term high blood sugar in diabetes leads to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves. Diabetic nephropathy is one of the most important and harmful complications of diabetes. It is the primary cause (about 44%) of end-stage renal disease in developed countries such as Europe and the United States, and the second cause of end-stage renal disease in my country. Its onset is hidden. Most of them can be reversed after treatment in the early stage, and end-stage renal disease will develop in the late stage. Nowadays, the incidence of diabetes and kidney disease ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/543G01N33/577G01N33/558
CPCG01N33/543G01N33/558G01N33/577
Inventor 胡容王忠亮吴才桂陈军超陈兴陈一凡
Owner ANHUI HUIBANG BIOLOGICAL ENG
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