Continuous production method of ethoxyquinoline

Abstract

The invention discloses a continuous production method of ethoxyquinoline. The method comprises the steps of continuously adding a raw material p-phenetidine liquid, an acid catalyst p-toluene sulfonic acid and half of liquid solvent methylbenzene for dehydration to the top of a tower reactor through a material distributing kettle; carrying out dehydration-condensation reaction on the obtained mixture and mixed steam of a raw material acetone steam and the other half of the solvent methylbenzene steam for azeotropic dehydration in the tower reactor; continuously discharging condensation products from the bottom of the tower and carrying out water washing and neutralization on the products; continuously discharging the water and a mixed gas of methylbenzene azeotropic steam and part of unreacted acetone steam which are produced in the reaction out of the reactor and condensing into liquid; continuously separating into a methylbenzene phase and a water phase; returning the methylbenzene to the system to recycle; and purifying the water solution containing part of acetone through rectification and recycling the acetone. The method disclosed by the invention has the advantages of increasing the production capacity of a single production line of the ethoxyquinoline, increasing the reaction efficiency and shortening the reaction time.

Description

technical field [0001] The invention relates to a continuous production method of ethoxyquinoline. Background technique [0002] At present, the production industry of ethoxyquinoline (6-ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline) generally adopts "acidic catalyst to catalyze the condensation dehydration of p-aminophenethyl ether and acetone Based on the "reaction" principle, the production process is basically an intermittent batch production process. The production capacity of a single production line is small, the investment per unit production capacity is high, the material consumption and energy consumption are high, the labor is large, and the labor intensity is high. It is difficult to achieve fully automatic control. The production The product has lower purity and unstable quality, and the technical and economic level has a large gap with the present invention. Contents of the invention [0003] The purpose of the present invention is to provide a kind of product...

AI Technical Summary

Problems solved by technology

[0002] At present, the production industry of ethoxyquinoline (6-ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline) generally adopts "acidic catalyst to catalyze the condensation dehydration of p-aminophenethyl ether and acetone Based on the "reaction" principle, the production process is basically an intermittent batch production process. The production capacity of a single production l