Unlock instant, AI-driven research and patent intelligence for your innovation.

Pharmaceutical compositions for treating arrhythmia and therapeutics of

A pharmaceutical composition and technology for arrhythmia, applied in the field of pharmaceutical composition for treating arrhythmia

Inactive Publication Date: 2017-09-19
GWOXI STEM CELL APPL TECH CO LTD
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] While there are treatments for arrhythmias, all of these treatments come with some sequelae

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pharmaceutical compositions for treating arrhythmia and therapeutics of
  • Pharmaceutical compositions for treating arrhythmia and therapeutics of
  • Pharmaceutical compositions for treating arrhythmia and therapeutics of

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] method

[0032] Chemical material

[0033] BP (A10353) was purchased from Alfa Aesar. Dissolve BP in dimethyl sulfoxide (DMSO; Sigma), shake at 25°C for 1 hour, and store at 4°C for later use.

[0034] Isolation of human ADSCs

[0035] In this example, the 3-5 generations of ADSCs were used (approved by the China Medical University Experimental Ethics Committee, provided by Guoxi Stem Cell Application Technology Co., Ltd. (Hsinchu, Taiwan)). These ADSCs are identical and do not contain endothelial cells or hematopoietic lineages. Cultured ADSCs have a mesenchymal stem cell phenotype: express the mesenchymal stem cell marker CD90, and will not express the hematopoietic markers CD31 and CD34. The cell characteristics are approved by the competent authority in Taiwan. In addition, hADSCs have been used in clinical trials of liver cirrhosis.

[0036] The cells were placed in cells containing 10% (v / v) FBS (fetal bovine serum), 10ng / ml bFGF (basic fibroblast growth factor, R&D Sy...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

This invention provides a pharmaceutical compositions for treating arrhythmia. The pharmaceutical compositions comprise stem cells, pretreated with n-butylidenephthalide (BP).

Description

Technical field [0001] The present invention provides a pharmaceutical composition for treating arrhythmia, wherein the pharmaceutical composition includes stem cells. Background technique [0002] Arrhythmia, also known as arrhythmia or arrhythmia, is an irregular heartbeat, such as too fast or too slow. Fast heartbeat, which refers to adults with a heartbeat of more than 100 beats per minute-is called tachycardia, and slow heartbeat, which refers to a heartbeat of less than 60 beats per minute-is called bradycardia. Many forms of arrhythmia have no symptoms. When symptoms occur, they may include palpitations or pauses in the heartbeat. More serious may cause dizziness, fainting, shortness of breath or chest pain. Most types of arrhythmia are not serious, and some people are prone to complications such as stroke or heart failure. Others may cause the heart to stop. [0003] Arrhythmia is mainly divided into 4 categories: extrasystole, supraventricular tachycardia, ventricular...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/06A61K35/28A61K33/00A61P9/06
CPCA61K9/0019A61K33/00A61K35/28A61K45/06A61K2300/00A61K31/404A61K31/5377A61P9/06
Inventor 李聪明庄明熙陈俊宏林珀丞李家昕
Owner GWOXI STEM CELL APPL TECH CO LTD