Medicinal preparation for promoting body surface wound healing and preparation method thereof
A pharmaceutical preparation and body surface technology, which is applied in the direction of pharmaceutical formulations, drug combinations, active ingredients of heterocyclic compounds, etc., can solve problems such as single action, lack of analgesic effect, and short duration of drug effect
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Embodiment 1
[0072] Embodiment 1: The influence of pharmaceutical preparation of the present invention on rat scald infected wound healing pigmentation
[0073] 1. Model copy:
[0074] The day before the experiment, rats were depilated on their backs: after shaving with a shaver, they were depilated with 10% sodium sulfide, and reared in a single cage.
[0075] The scald model adopts YLS-5Q desktop super temperature-controlled scald instrument, 3# vertebral scald head, 100°C, 15 seconds, pressure 500g, touching the skin, causing an area of 4cm on the back of the rat 2 , burn wounds from 2 degrees deep to 3 degrees superficial.
[0076] After 10 minutes, smear 0.2ml / rat's MRSA bacterial solution on the wound surface of rats (the amount of bacteria is 10 9 CFU / ml), 4 hours after the bacterial solution was applied, the drug was given to start the treatment.
[0077] 2. Experimental records:
[0078] During the experiment, the wound was photographed on the 14th day, and it can be seen th...
Embodiment 2
[0091] Embodiment 2: the effect of pharmaceutical preparation on wound healing of rat scald infection
[0092] 1. Model copy:
[0093]The day before the experiment, rats were depilated on their backs: after shaving with a shaver, they were depilated with 10% sodium sulfide, and reared in a single cage.
[0094] The scald model adopts YLS-5Q desktop super temperature-controlled scald instrument, 3# vertebrae, 100°C, 15 seconds, 500 grams of pressure, touching the skin, causing an area of 4cm on the back of the rat 2 , burn wounds from 2 degrees deep to 3 degrees superficial.
[0095] After 10 minutes, smear 0.2ml / only Pseudomonas aeruginosa bacterium liquid on rat wound surface (bacterial amount is 10 9 CFU / ml), 4 hours after the bacterial solution was applied, the drug was given to start the treatment.
[0096] 2. Experimental records:
[0097] During the experiment, the burn area was measured every 7 days, and the scab formation time was recorded, and the experiment was...
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