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Oral rehydration composition and methods thereof

一种组合物、补液的技术，应用在药物组合、含无机化合物食品配料、血液疾病等方向，能够解决不理想电解质性质、改变、含水产品被污染等问题

Active Publication Date: 2017-09-26
TONISTER INT LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These practices may result in reconstituted aqueous products that may be contaminated or have altered, undesirable electrolyte properties

Method used

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  • Oral rehydration composition and methods thereof
  • Oral rehydration composition and methods thereof
  • Oral rehydration composition and methods thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0128] Administer oral rehydration therapy

[0129] The oral rehydration solution of the present invention may be administered orally at an initial rate of about 0.5 ml / kg every 2 hours, using a syringe if desired. This is a very small volume and rarely causes vomiting. This amount may be increased by 50% every 8-12 hours if vomiting does not occur. For cats and puppies, ice cube trays can be used to freeze small pieces of the oral rehydration solution and dispensed as needed. Once the patient begins to lick fluids, the volume can be increased rapidly and more calorie-dense foods can be introduced. Oral rehydration therapy also has a place in the outpatient treatment of a variety of other conditions. Oral rehydration therapy, especially if it is a highly palatable product such as the oral liquid rehydration formulation of the present invention, may be used as part of a dietary management program for patients with mild gastroenteritis. In many of these patients, a short per...

Embodiment 2

[0132] The embodiment of the oral rehydration solution preparation of hydrolyzed wheat protein source according to the present invention is as follows:

[0133] Element

in %

water

96.27

Glucose monohydrate

1.50

Sodium chloride

0.26

potassium chloride

0.15

Glycine

0.40

trisodium citrate

0.29

xanthan gum

0.05

Hydrolyzed Wheat Protein

1.00

L-glutamic acid

0.04

monosodium glutamate

0.04

[0134] Concentrate Formulation of Example 2

[0135] Concentrates can be prepared as follows:

[0136]

[0137]

[0138] The concentrate was mixed and kept at room temperature for at least 5 minutes. Typically, after 10x dilution, the pH is about 3.7 to 3.8 at 20°C and ready to use. For diluted use, add 10ml of the concentrate to 90ml of water and mix.

Embodiment 3

[0140] Oral liquid rehydration formulation for pigs, calves and lambs

[0141] The embodiment of the oral rehydration solution preparation of hydrolyzed wheat protein source according to the present invention is as follows:

[0142] Element

in %

water

96.27

Glucose monohydrate

1.50

Sodium chloride

0.26

potassium chloride

0.15

Glycine

0.40

Sodium dihydrogen phosphate

0.10

xanthan gum

0.05

Hydrolyzed Wheat Protein

1.00

L-glutamic acid

0.04

monosodium glutamate

0.04

[0143] Concentrate Formulation of Example 3

[0144] Concentrates can be prepared as follows:

[0145]

[0146]

[0147] The concentrate was mixed and kept at room temperature for at least 5 minutes. Typically, after 10x dilution, the pH is about 3.7 to 3.8 at 20°C and ready to use. For diluted use, add 10ml of the concentrate to 90ml of water and mix.

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PUM

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Abstract

An oral rehydration composition comprising the following: 1-glutamic acid in a range of about 0.01% to about 0.40% w / w and monosodium glutamate in a range of about 0.05% to about 0.80% w / w; about 1.50% w / w glucose monohydrate; about 0.20% w / w sodium chloride; about 0.15% w / w potassium chloride; about 0.35% w / w glycine; about 0.30% w / w trisodiumcitrate; about 0.15% w / w sodium dihydrogen phosphate; about 0.10% w / w xanthan gum; 85% Steviol Glycoside extract in a range of about 0.01% to about 0.03% w / w; about 0.20% w / w citric acid monohydrate; hydrolyzed whey in a range of about 0.15% to about 1.00% w / w; about 1.00% w / w hydrolyzed wheat; comprises cereals as a protein source; comprises enzyme co- factors; comprises a monosaccharide. The oral rehydration composition can be used on humans or animals that suffer from diarrhea.

Description

technical field [0001] The present invention relates to an oral rehydration product for use in the treatment of mammals suffering from gastrointestinal disorders which may be of nutritional, parasitic, prion, bacterial, viral or protozoal etiology and result in fluid depletion , Acidosis, essential electrolyte imbalance or loss. These diseases cause more severe clinical signs in young animals and children but can occur in any adult species. Dehydration and electrolyte imbalance can lead to death. Background technique [0002] normal digestion [0003] The functional goal of digestion is to break down complex foods into small components (nutrients) that can be absorbed by the intestine into the body, where the nutrients can be reassembled into the complex molecules necessary to perform the body's normal metabolism. The main three types of nutrients are proteins, carbohydrates and fats, which are decomposed into amino acids, sugars and lipids respectively. Water and electr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/175A23L33/125A23L33/16A23L33/10A23L33/18A23K20/142A23K20/163A23K20/26A23K20/105A23K10/28A23K10/30
CPCA23V2002/00A23L33/175A61P1/00A61P3/02A61P43/00A61P7/08A23V2200/32A23V2250/032A23V2250/0618A23V2250/0622A23V2250/16A23V2250/1614A23V2250/262A23V2250/5086A23V2250/5482A23V2250/55A23K20/142A61K31/195
Inventor 阿龙·罗森堡亚伯拉罕·米尔斯坦安东尼·麦克尔埃娃·玛丽·费尔斯米歇尔·施瓦兹·莫妮克西蒙·范·达尔森阿里·哈尔彭
Owner TONISTER INT LTD
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