Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Application of hydrogen molecule liquid/gas in preparation of drugs for inhibiting tumor stem cells

A technology of tumor stem cells and hydrogen molecules, applied in the application field of hydrogen molecule liquid/gas in the preparation of drugs for inhibiting tumor stem cells

Inactive Publication Date: 2017-10-24
BEIJING UNIV OF TECH
View PDF4 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, whether hydrogen or hydrogen-rich water can inhibit tumor stem cells is still not reported

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of hydrogen molecule liquid/gas in preparation of drugs for inhibiting tumor stem cells
  • Application of hydrogen molecule liquid/gas in preparation of drugs for inhibiting tumor stem cells
  • Application of hydrogen molecule liquid/gas in preparation of drugs for inhibiting tumor stem cells

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Preparation of hydrogen-containing medium in cell culture

[0023] 1. After the magnesium rod is autoclaved, it is placed in the cell culture medium. After two days, the hydrogen concentration in the medium reaches saturation and is ready for use.

[0024] 2. The 100% volume ratio pure hydrogen generated by electrolyzed water is passed into the medium for a certain period of time (50mL 30min), at which point the hydrogen concentration in the medium reaches saturation and is ready for use.

[0025] (2) Treatment of hydrogen group in animal glioma model

[0026] 1. In the animal model of the breathing hydrogen group, hydrogen is generated by electrolyzing water, and the mixed gas containing 60% hydrogen and air is passed into the animal incubator for the animals to breathe.

[0027] 2. In the animal model of drinking hydrogen-rich water, the experimental animals drink hydrogen-rich water containing saturated hydrogen molecules. Hydrogen-rich water is prepared by ele...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides an application of hydrogen molecule liquid / gas in preparation of drugs for inhibiting tumor stem cells, belonging to the technical field of preparation of drugs for inhibiting tumor stem cells. By applying the liquid / gas containing hydrogen molecules in preparation of drugs for inhibiting tumor stem cells, the tumor formation capability in tumors is obviously inhibited, the invasion ability of tumor cells is obviously reduced, the expression of surface markers CD133 of tumor stem cells is obviously inhibited, and the expression of differentiation markers is promoted.

Description

technical field [0001] The invention belongs to the technical field of preparation of drugs for inhibiting tumor stem cells, and in particular relates to the application of hydrogen molecule liquid / gas in the preparation of drugs for inhibiting tumor stem cells. technical background [0002] In recent years, as studies have found that tumors are not composed of uniform tumor cells, different cells in tumors have different abilities to proliferate, invade and metastasize, and have strong heterogeneity. A small part of the cells has the potential of self-renewal, unlimited proliferation and multi-directional differentiation. These cells are called cancer stem cells (CSC). Tumors and the initial cells that initiate the rapid proliferation of tumors can also produce new tumor cells through continuous differentiation to form complete tumors. Cancer stem cells are also considered to be the culprit of drug resistance and recurrence, and finding effective drugs to inhibit glioma st...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K33/00A61P35/00
CPCA61K33/00A61K2300/00
Inventor 马雪梅刘梦昱阎新龙谢飞赵鹏翔商蕾王婷婷
Owner BEIJING UNIV OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com