Application of common cephalanoplos herb total flavones in preparation of medicine used for treating repeated cerebral ischemia and focal cerebral ischemia

Abstract

The invention relates to application of common cephalanoplos herb total flavones in preparation of a medicine used for treating repeated cerebral ischemia and focal cerebral ischemia. The problem that the common cephalanoplos herb total flavones are taken as a unique active ingredient for preparing the repeated cerebral ischemia and focal cerebral ischemia can be effectively solved. The common cephalanoplos herb total flavones are obtained by smashing common cephalanoplos herb into coarse powder, carrying out reflux extraction and degreasing by virtue of diethyl ether, volatilizing diethyl ether from medicine residue, adding 80% ethanol and soaking, carrying out reflux extraction, filtering, carrying out reduced pressure ethanol recovery on filtrate until no alcohol flavor is left, adding distilled water, dispersing into dispersion liquid equivalent to containing crude drug according to a ratio of 0.3g / mL, loading the dispersion liquid on an AB-8 type macroporous adsorption resin, sequentially eluting with the distilled water, 10% ethanol and 80% ethanol, collecting 80% ethanol eluent, carrying out reduced pressure ethanol recovery until no alcohol flavor is left, carrying out freeze drying, and smashing, so that the common cephalanoplos herb total flavones are obtained. The application provided by the invention has the advantages that extraction of the common cephalanoplos herb total flavones from the common cephalanoplos herb can be effectively solved, the common cephalanoplos herb total flavones can be effectively used for treating the repeated cerebral ischemia and focal cerebral ischemia, new application and pharmaceutical value of the common cephalanoplos herb are developed, and obvious economic and social benefits are realized.

Description

technical field [0001] The invention relates to medicine, in particular to the application of total flavonoids of thistle in the preparation of medicines for treating repeated cerebral ischemia and focal cerebral ischemia. Background technique [0002] Cerebral ischemic diseases are a group of diseases in which blood supply to the brain, cerebellum or brainstem is insufficient in one or more parts due to various reasons, thereby causing corresponding neurological symptoms. Including repeated cerebral ischemia and focal cerebral ischemia, the etiology of formation is complex, repeated cerebral ischemia refers to repeated attacks of cerebral ischemia; focal cerebral ischemia refers to transient ischemic attack (TIA), carotid or Transient insufficiency of blood supply in the vertebral-basilar artery system causes focal cerebral ischemia leading to sudden, transient and reversible neurological dysfunction. The attack lasts for several minutes, and usually recovers completely wi...

AI Technical Summary

Problems solved by technology

But so far there is no application of the total flavonoids extracted from thistle in the preparation of drugs for the treatment of repeated cerebral ischemia and focal cerebral ischemia

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