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Traditional Chinese medicine composition and applications thereof

A composition and technology of traditional Chinese medicine are applied in the field of traditional Chinese medicine compositions containing various plant polysaccharides and plant oils to achieve the effects of improving the immune function of the body, restoring the immune monitoring function, and reducing the expression rate of positive cells

Inactive Publication Date: 2017-12-15
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above three conventional treatment methods all have certain limitations and cause certain pain to the patients, especially radiotherapy and chemotherapy also have different degrees of inhibition on the normal immune system.

Method used

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  • Traditional Chinese medicine composition and applications thereof
  • Traditional Chinese medicine composition and applications thereof
  • Traditional Chinese medicine composition and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1, the preparation of Ganoderma lucidum polysaccharide

[0031] The Ganoderma lucidum polysaccharide of the present invention is prepared by the following preparation method: after pulverizing the Ganoderma lucidum, add water according to the weight ratio of Ganoderma lucidum:water=1:10, heat and stir at 70°C for 2 hours, and filter the obtained filter residue according to the above-mentioned ratio of solid to liquid, Continue to extract twice at temperature and time, combine three extractions, concentrate under reduced pressure and centrifuge to obtain a clarified concentrate, add 7 times the volume of 95% ethanol to the clarified concentrate according to the volume ratio of clarified concentrate: 95% ethanol=1:7 After mixing, let it stand overnight at 4°C to precipitate, centrifuge to collect the precipitate, and vacuum freeze-dry to obtain Ganoderma lucidum polysaccharide.

Embodiment 2

[0032] Embodiment 2, the preparation of Grifola frondosa polysaccharide

[0033] The frondosa frondosa polysaccharide of the present invention is prepared by the following preparation method: after pulverizing the frondosa frondosa, add water according to the weight ratio of frondosa frondosa: water = 1:5, heat and stir at 75°C for 3 hours, and filter the obtained filter residue Continue to extract twice according to the above-mentioned solid-liquid ratio, temperature and time, combine the extracts three times, concentrate under reduced pressure and centrifuge to obtain a clarified concentrate, according to the volume ratio of the clarified concentrate: 95% ethanol=1:9, 9 times the volume of 95 % ethanol was added to the clarified concentrated solution, and after mixing, it was allowed to stand overnight at 4°C to precipitate, and the precipitate was collected by centrifugation, and vacuum freeze-dried to obtain Grifola frondosa polysaccharide.

Embodiment 3

[0034] Embodiment 3, the preparation of angelica oil

[0035] The angelica oil of the present invention is prepared by the following preparation method: take 400g of angelica fine powder (10 mesh), add 15 times the weight of water and mix evenly, so that the ratio of material to liquid reaches 1:15, soak for 5h and extract by steam distillation, During the extraction process, add sodium chloride (80g) which is 1 / 5 of the amount of Angelica sinensis. The extraction temperature is 140-150°C, the steam flux is 2L / h, and the extraction time is 8 hours. The essential oil of Angelica sinensis is light yellow and has the unique aroma and bitter taste , the yield is 0.2-0.3%, and stored in a refrigerator at -20°C.

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Abstract

The invention belongs to the field of drugs and health-care food, and discloses a traditional Chinese medicine composition, which contains ganoderma lucidum polysaccharides, grifola frondosa polysaccharides, angelica sinensis oil and cinnamon oil. Experiments show that the prepared traditional Chinese medicine composition is scientifically combined, brings out the best in each other, has no toxic and side effects, not only has nutritional values, but also can inhibit the growth of tumors, remarkably increase the percentage of CD<4+> and CD<8+> cells in tumor stroma lymphocyte compared with single component, enhance the organism immunity function, restore the normal immune monitoring function of the organism, reduce the expression rate of mice tumor tissue VEGF and TGF-beta1 positive cells, help treat tumors, enhance the anti-tumor effect of chemotherapeutic drugs, and improve the organism immunity condition, has the function of restoring the normal immune monitoring of the organism, and can play a role in preventing and / or help treating tumors.

Description

technical field [0001] The invention belongs to the field of medicine and health food, and in particular relates to a traditional Chinese medicine composition and its application, in particular to a traditional Chinese medicine composition containing various plant polysaccharides and vegetable oils and its application. Background technique [0002] Tumor refers to the new organism formed by the proliferation of local tissue cells under the action of various tumorigenic factors. According to the size and growth characteristics of tumors that are harmful to the human body, they are divided into two categories: benign tumors and malignant tumors. Benign tumors grow slowly, showing expansive growth, and often have a complete capsule on the surface. Except for local symptoms, they have few systemic symptoms, do not infiltrate to surrounding tissues and do not metastasize to the whole body. They are not easy to recur after surgical resection, and are less harmful to the body, such...

Claims

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Application Information

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IPC IPC(8): A61K36/54A61P35/00A61P37/04A61P39/00A61P43/00A23L33/00A61K31/715
CPCA23L33/00A61K31/715A61K36/232A61K36/54A23V2002/00A61K2236/39A61K2236/37A61K2236/53A61K2236/51A61K2236/331A61K2300/00A23V2200/308A23V2200/324A23V2250/21A23V2250/208A61K36/07A61P37/02A61P35/00A61K36/074A61K2236/15
Inventor 胡明华马方励王园园马忠华从仁怀肖凌云
Owner INFINITUS (CHINA) CO LTD
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