Traditional Chinese medicine composition for treating thrombocytopenia and its preparation method and application

Abstract

The invention discloses a traditional Chinese medicine composition for treating thrombocytopenia and a preparation method and an application thereof. The traditional Chinese medicine composition is mainly prepared by mixing deer blood and peanut coat according to the weight ratio of (2-20):1. The deer blood is treated by the viral inactivation treatment and the freeze-drying treatment. In the treatment process, in order to guarantee that protein is not denaturalized because of the high temperature, the temperature does not exceed 50 DEG C, and in order to improve the utilization ration of drugs and the absorption rate by a human body, the liquid-state deer blood is made as the solid-state by using a freeze-drying mode. The peanut coat is concrete-like peanut coat aqueous extract obtained by boiling and concentrating the peanut coat and water, so the administration volume of the peanut coat is reduced by a hundred times through the processing, and medicinal compositions are not lost. The traditional Chinese medicine composition has the functions of tonifying deficiency and replenishing essence and blood, is capable of forming various dosage forms of the traditional Chinese medicinepreparations by adding other pharmaceutically acceptable accessory materials, and is used for treating the thrombocytopenia after chemotherapy without the side effect. In addition, the utilization ratio of the drug is high, and the preparation, administration and carriage are convenient.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation method and application, in particular to a traditional Chinese medicine composition for treating thrombocytopenia, its preparation method and application, and belongs to the field of traditional Chinese medicine pharmacy. Background technique [0002] Thrombocytopenia is a common disease in clinical hematology, and its etiology is often caused by radiotherapy, chemotherapy, or idiopathic thrombocytopenic purpura, among which chemotherapy is the main cause of thrombocytopenia. Thrombocytopenia after chemotherapy Symptoms such as dizziness, fatigue, fatigue, soreness of the waist and knees, and loss of appetite often occur in patients with dysentery. The reason for chemotherapy-induced thrombocytopenia is that chemotherapy is currently one of the effective methods for treating tumors. Due to the non-selective cell killing effect of anti-tumor drugs, chemotherapy damag...

AI Technical Summary

Problems solved by technology

Many chemotherapy drugs (such as carboplatin, gemcitabine, mitomycin, cyclophosphamide, doxorubicin, etc.) can cause thrombocytopenia, combined chemotherapy is more likely to increase the incidence of thrombocytopenia, so thrombocytopenia caused by chemotherapy Symptoms greatly affect the progress of chemotherapy and the follow-up treatment of patients, and even affect the lives of patients

At present, Western medicine uses platelet transfusion as the standard treatment, but due to the limited storage time of platelets, lack of blood supply, high cost, and the possibility of blood-borne infections, blood transfusion reactions, and platelet antibody production, clinical application is limited; clinical drugs mainly It consists of adrenocortical hormone, immunosuppressant, etc., but the above-mentioned drugs have serious adverse reactions when used, and patients often cannot tolerate them; there are also biological types of drugs such as thrombopoietin (TPO) and IL-6, etc., although the curative effect is good and Few side effects, but its price is very expensive, ordinary consumers can not afford it, which limits the wide clinical application

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