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oral care composition

A technology of oral care and composition, which is applied in the field of oral care composition, and can solve problems such as not helping teeth remineralization, damage to teeth and gums, etc.

Active Publication Date: 2021-05-11
UNILEVER IP HLDG BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These types of products are often undesirable because they do not help remineralize teeth and, if used in excess, can cause damage to teeth and gums

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0122] This example demonstrates the improvement in deposition on tooth surfaces by using calcium silicate in combination with a deposition aid. All ingredients are expressed as percent by weight of the total formulation and expressed as the level of active ingredient.

[0123] Table 1

[0124]

[0125] a. Commercially available calcium silicate (CaSiO 3 )(Sorbosil CA40)

[0126] method

[0127] To evaluate deposition on tooth surfaces, test samples were mixed with water to make a slurry at a ratio of 5 g of test sample to 10 ml of water. Sample 1 containing commercially available calcium silicate (CS) and glycerin was used as a control.

[0128] Following the same protocol, the bovine enamel blocks were treated with different slurries by brushing. The enamel blocks were brushed with the slurry under a toothbrush equipped with a toothbrush. The tooth brushing load was 170g + / - 5g, and the automatic brushing was operated at a speed of 150rpm. After brushing for 1 ...

Embodiment 2

[0135] This example demonstrates improved sealing of dentinal tubules by use of calcium silicate in combination with a deposition aid. All ingredients are expressed as percent by weight of the total formulation and expressed as the level of active ingredient.

[0136] table 3

[0137]

[0138] b. Commercially available silica abrasives (SiO 2 )(Zeodent 124)

[0139] c. Commercially available silica abrasives (SiO 2 )(Sorbosil AC43)

[0140] method

[0141] To evaluate the sealing efficacy on the dentinal tubules, the test samples were mixed with water at a ratio of 1 g of test sample to 2 mL of water to make a slurry. Sample 4 containing only commercial calcium silicate was used as a control.

[0142] Dentin samples were treated with different slurries by brushing following the same protocol. Dentin samples were brushed with the slurry under a toothbrush machine equipped with a toothbrush. The tooth brushing load was 170g + / - 5g and the automatic brushing was oper...

Embodiment 3

[0147] This example demonstrates the improvement in tooth whitening efficacy by the use of high refractive index particles in the presence of calcium silicate (CS) and deposition aids.

[0148] Table 4

[0149]

[0150] d. Commercially available calcium silicate coated titanium dioxide from the company KOBO Products

[0151] method

[0152] a. Scrubbing Protocol for Samples Containing CS and Deposition Aids (except Calcium Phosphate)

[0153] To examine the whitening effect of the samples, a fresh slurry was prepared by mixing the test sample with water at a ratio of 1.5 g of the test sample to 10 mL of water for 20 seconds and used immediately.

[0154] Following the same protocol, the bovine enamel blocks were treated with different slurries by brushing. The enamel blocks were brushed with the slurry under a toothbrush equipped with a toothbrush. The tooth brushing load was 170g + / - 5g and the automatic brushing was operated at a speed of 150rpm. After brushing...

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Abstract

Disclosed is an oral care composition comprising calcium silicate, a deposition aid selected from calcium sulfate hemihydrate, calcium dihydrogen phosphate or mixtures thereof, and a physiologically acceptable carrier, wherein the calcium silicate and the deposition aid are present in a weight ratio of 20:1 to 1:5.

Description

technical field [0001] The present invention relates to oral care compositions such as toothpaste, chewing gum, mouthwash and the like. In particular, the present invention relates to oral care compositions comprising calcium silicate and deposition aids which lead to remineralization and / or reduction of sensitivity and / or whitening of teeth. The invention also relates to the use of such compositions for remineralizing and / or reducing sensitivity and / or whitening the teeth of an individual. Background technique [0002] The enamel layer of teeth is naturally opaque white or off-white. However, this enamel layer may stain or discolor. [0003] Many products we consume have negative effects on our teeth and mouth. Acidic drinks and sweets, for example, can cause tooth erosion by eroding the enamel, the outer coating that protects teeth. In addition, tobacco-based products and beverages like coffee and tea can stain or reduce the whiteness of teeth. These staining and disc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/25A61K8/24A61K8/19A61Q11/00
CPCA61K8/19A61K8/24A61K8/25A61Q11/00A61K8/26
Inventor A·乔伊纳李小科刘炜宁
Owner UNILEVER IP HLDG BV
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