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Method and apparatus for assisting diagnosis of risk of progression to stage 2 or higher diabetic nephropathy

A technology for diabetic nephropathy and diabetes, which can be used in measurement devices, disease diagnosis, material inspection products, etc., and can solve problems such as reducing medical expenses

Inactive Publication Date: 2018-04-03
SYSMEX CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition, it contributes greatly to the reduction of medical expenses

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  • Method and apparatus for assisting diagnosis of risk of progression to stage 2 or higher diabetic nephropathy
  • Method and apparatus for assisting diagnosis of risk of progression to stage 2 or higher diabetic nephropathy
  • Method and apparatus for assisting diagnosis of risk of progression to stage 2 or higher diabetic nephropathy

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Embodiment approach

[0030] In the diagnosis method of the present embodiment, a diabetic patient (hereinafter, also referred to as "test subject") of the first stage of diabetic nephropathy is targeted for diagnosis. Diabetic nephropathy stage 1 means that the classification of albuminuria in the severe classification of chronic kidney disease (CKD) recorded in KDIGO (Kidney Disease: Improving Global Outcoms) 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease is A1, and GFR distinguishes the disease stages as G1, G2, G3a or G3b. A diabetic patient with stage 1 diabetic nephropathy is a patient diagnosed with diabetes, with a urine albumin / creatinine (Cr) ratio of less than 30 mg / gCr, and an estimated GFR of 30 mL / min / 1.73m 2 above patients. The first stage of diabetic nephropathy is also called pre-nephropathy, and there is no medical opinion of kidney disease and no subjective symptoms. The method for diagnosing diabetes is not particularly limited, an...

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Abstract

Disclosed is a method for assisting diagnosis of the risk of progression to stage 2 or higher diabetic nephropathy for a diabetic patient with stage 1 diabetic nephropathy, comprising measuring urinary apolipoprotein E (ApoE) concentration of a diabetic patient with stage 1 diabetic nephropathy, and determining whether the patient has a high risk of progressing to stage 2 or higher diabetic nephropathy based on a result of the measurement step.

Description

【Technical field】 [0001] The present invention relates to a method and a device for assisting in diagnosing the risk of developing from the first stage of diabetic nephropathy to the second stage of diabetic nephropathy and beyond. 【Background technique】 [0002] Diabetic nephropathy is one of the complications of diabetes and is a kidney disease that develops through stages. The disease stage of diabetic nephropathy is classified into 5 stages of diabetic nephropathy 1 to 5 stages. Diabetic nephropathy develops, eventually leading to renal failure, and dialysis treatment becomes necessary. Dialysis treatment is a great burden on patients. In recent years, the number of patients requiring dialysis treatment has increased, and the accompanying increase in medical expenses has become a problem. [0003] In diabetic nephropathy, if appropriate treatment can be initiated at an early stage, renal function can be restored. However, at a further stage, even if the progression o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/68
CPCG01N33/6893G01N2800/50G01N2800/042G01N2333/775G01N2800/347G01N33/92G01N2800/52G01N2800/56
Inventor 白波濑泰史吉田敏之
Owner SYSMEX CORP