Electrode device for inactivating tumor cells in esophageal wall and method of using the same

Abstract

The invention relates to the field of medical equipment, in particular to an electrode device for inactivating tumor cells in the esophageal wall and a using method thereof. The electrode device includes a worktable and a push tube, the push tube matches with a ring electrode arranged inside the push tube, and a wire of the ring electrode penetrates from the upper portion of the push tube and is connected with a power distribution controller on the worktable. The objective is to provide the electrode device for inactivating the tumor cells in the esophageal wall and the using method thereof, the ring electrode is used as a working part, the push tube is used as a delivery medium, a special device use mode is applied, and the tumor cells in the surrounding esophageal wall can be inactivatedby an electric field generated by a direct current high voltage.

Description

technical field [0001] The invention relates to the field of medical equipment, in particular to an electrode device for inactivating tumor cells in the esophagus wall and its application method. Background technique [0002] Irreversible electroporation (irreversible electroporation, IRE) is a new soft tissue ablation technology, which uses ultra-short high-voltage direct current (up to 3 kV) to generate multiple nanoscale micropores on the cell membrane of cells in the ablated tissue, irreversible Disrupts the balance in cells, induces apoptosis and eventually dies. [0003] The device for irreversible electroporation is mainly composed of a high-voltage pulse power supply, a power distribution controller composed of an oscilloscope, and electrodes. [0004] The electrode is used to apply DC high voltage to the tissue cells. Currently, the widely used electrode is the needle electrode. The electrode needle is inserted into the tissue and forms a high-voltage electric fiel...

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Problems solved by technology

[0004] The electrode is used to apply DC high voltage to the tissue cells. Currently, the widely used electrode is the needle electrode. The electrode needle is inserted into the tissue and forms a high-voltage electric field around it, that is, the ablation zone, thereby inactivating the tissue cells in a specific area. In some animal experiments, flat-plate electrodes are used. However, both needle electrodes and flat-plate electrodes are only used in clinical treatment or experiments of solid tumor tissues such as liver cancer, pancreatic cancer, prostate cancer, and kidney cancer. For esophagus Cancer, a tumor in a hollow organ, cannot be treated with either electrode

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