Nocturia active medicinal solution and preparation method thereof

Abstract

The invention discloses nighttime frequent micturition acting medicinal liquid. The medicinal liquid comprises, by weight, 12 parts of the dried fruit of rubus chingii Hu, 12 parts of the seed of Chinese dodder, 12 parts of the fruit of Chinese wolfberry, 12 parts of the dried fruit of rosa laevigata, 12 parts of the fruit of glossy privet, 15 parts of the root of astragalus mongholicus, 12 partsof the root of salvia miltiorrhiza, 12 parts of the dried root of Radix paeoniae Alba, 5 parts of honey-fried licorice root, 15 parts of the prepared tuber of polygonum multiflorum, 24 parts of herbaepimedii and 1 part of the dried bark of cinnamomum cassia; the content of icariin of every bottle of the medicinal liquid is no less than 6.0 mg, and the amount of specnuezhenide is no less than 5.0mg. The invention also provides a preparation method for the nighttime frequent micturition acting medicinal liquid. By means of the nighttime frequent micturition acting medicinal liquid and the preparation method thereof, liquid precipitation can be reduced, the content of active ingredients of the icariin, the specnuezhenide and the like is effectively improved, and curative effects are improved.

Description

technical field

[0001] The invention relates to the technical field of biopharmaceuticals, in particular to a nocturia action medicinal liquid and a preparation method thereof. Background technique

[0002] With the increasing social pressure and the accelerated pace of life, the continuous deterioration of the environment, and bad eating habits, our unhealthy and sub-healthy conditions are also increasing day by day.

[0003] Nocturia refers to an increase in the frequency of urination at night, more than 3 times; or an increase in urine output at night, exceeding 1 / 4 of the total daily urine output. It belongs to "syndrome of deficiency of kidney qi" and belongs to the category of "deficiency disease" in traditional Chinese medicine. Nocturia is mostly a frequently-occurring disease of middle-aged and elderly people, a common disease. After the 40th day of life, the kidney qi gradually declines, the bladder loses its warmth, and cannot be properly qiized, resulting in lo...

Examples

Embodiment 1

[0060] 1. the preparation method of nocturia action medicinal liquid of the present invention is as follows:

[0061] (1) take epimedium by weight, add equal multiples of concentration and be 65% ethanol to soak, add water to decoct 3 times afterwards, wherein add 14 times of amount of water to decoct for the first time, separate decoction and dregs of medicine, Add 12 times the amount of water to the medicinal residues for decoction for the second time, separate the decoction and medicinal residues, add 10 times the amount of water to the medicinal residues for decoction for the third time, separate the decoction and medicinal residues, and combine the three decoctions , filter, and concentrate the filtrate under reduced pressure until every 1 mL is equivalent to 1 g of crude drug, add ethanol to the concentrated solution under reduced pressure until the alcohol content reaches 65%, stir evenly, let stand, filter, and take the supernatant Ⅰ;

[0062] (2) taking Ligustrum luci...

Embodiment 2

[0095] The preparation method, identification and content determination method of the nocturia action medicinal liquid are the same as in Example 1.

[0096] Through differential detection, medlar, astragalus, white peony root, licorice, and fleece-flower root were detected.

[0097] The content of icariin determined in each oral solution was 9.1 mg.

[0098] The content of privetin was determined to be 7.1 mg in each oral liquid.

Embodiment 3

[0100] The preparation method, identification and content determination method of the nocturia action medicinal liquid are the same as in Example 1.

[0101] Through differential detection, medlar, astragalus, white peony root, licorice, and fleece-flower root were detected.

[0102] The content of icariin determined in each oral liquid is 8.9mg.

[0103] The content of privetin was determined to be 7.3 mg in each oral liquid.

technical field

[0001] The invention relates to the technical field of biopharmaceuticals, in particular to a nocturia action medicinal liquid and a preparation method thereof. Background technique

[0002] With the increasing social pressure and the accelerated pace of life, the continuous deterioration of the environment, and bad eating habits, our unhealthy and sub-healthy conditions are also increasing day by day.

[0003] Nocturia refers to an increase in the frequency of urination at night, more than 3 times; or an increase in urine output at night, exceeding 1 / 4 of the total daily urine output. It belongs to "syndrome of deficiency of kidney qi" and belongs to the category of "deficiency disease" in traditional Chinese medicine. Nocturia is mostly a frequently-occurring disease of middle-aged and elderly people, a common disease. After the 40th day of life, the kidney qi gradually declines, the bladder loses its warmth, and cannot be properly qiized, resulting in lo...

Examples

Embodiment 1

[0060] 1. the preparation method of nocturia action medicinal liquid of the present invention is as follows:

[0061] (1) take epimedium by weight, add equal multiples of concentration and be 65% ethanol to soak, add water to decoct 3 times afterwards, wherein add 14 times of amount of water to decoct for the first time, separate decoction and dregs of medicine, Add 12 times the amount of water to the medicinal residues for decoction for the second time, separate the decoction and medicinal residues, add 10 times the amount of water to the medicinal residues for decoction for the third time, separate the decoction and medicinal residues, and combine the three decoctions , filter, and concentrate the filtrate under reduced pressure until every 1 mL is equivalent to 1 g of crude drug, add ethanol to the concentrated solution under reduced pressure until the alcohol content reaches 65%, stir evenly, let stand, filter, and take the supernatant Ⅰ;

[0062] (2) taking Ligustrum luci...

Embodiment 2

[0095] The preparation method, identification and content determination method of the nocturia action medicinal liquid are the same as in Example 1.

[0096] Through differential detection, medlar, astragalus, white peony root, licorice, and fleece-flower root were detected.

[0097] The content of icariin determined in each oral solution was 9.1 mg.

[0098] The content of privetin was determined to be 7.1 mg in each oral liquid.

Embodiment 3

[0100] The preparation method, identification and content determination method of the nocturia action medicinal liquid are the same as in Example 1.

[0101] Through differential detection, medlar, astragalus, white peony root, licorice, and fleece-flower root were detected.

[0102] The content of icariin determined in each oral liquid is 8.9mg.

[0103] The content of privetin was determined to be 7.3 mg in each oral liquid.

Images