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Extraction method for promoting abstraction effect on triterpene ingredient in antrodia camphorata

A triterpenoid extraction technology, which is applied to medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, pharmaceutical formulas, etc., can solve the problem that the total content of triterpenoids needs to be increased to prevent damage Effect

Inactive Publication Date: 2018-06-22
福州迈康医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The existing Antrodia camphorata extraction method is an organic solvent extraction method, using organic solvents such as alcohols, lipids, alkanes and haloalkanes as the extraction solvent to infiltrate the raw medicinal materials of Antrodia camphorata, and then remove the organic solvent by low-temperature distillation to obtain Antrodia camphorata extract, but the total content of triterpenoids extracted by this method still needs to be improved

Method used

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  • Extraction method for promoting abstraction effect on triterpene ingredient in antrodia camphorata
  • Extraction method for promoting abstraction effect on triterpene ingredient in antrodia camphorata

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Effect test

Embodiment 1

[0027] An extraction method for improving the extraction effect of triterpenoids in Antrodia camphorata, comprising the following steps:

[0028] A, after cleaning and drying the appearance of the fruit body of Antrodia camphorata, pulverize by a high-speed universal pulverizer, and sieve to obtain bacterial powder;

[0029] B. Take the bacteria powder, put it into 4.5% salt treatment solution and soak for 5 hours, take it out and dry it, then soak it in the traditional Chinese medicine treatment solution for 18 hours;

[0030] C. Pour the soaked bacteria powder into the ethanol solution, and carry out microwave oscillation to obtain the extract of Antrodia camphorata.

[0031] In described step A, cross 600 mesh sieves.

[0032] The traditional Chinese medicine treatment liquid includes the following components by weight percentage:

[0033] Glycerin 0.8%

[0034] Pine Pollen 0.3%

[0035] water balance.

[0036] In the step C, the volume content of ethanol in the ethano...

Embodiment 2

[0039] An extraction method for improving the extraction effect of triterpenoids in Antrodia camphorata, comprising the following steps:

[0040] A, after cleaning and drying the appearance of the fruit body of Antrodia camphorata, pulverize by a high-speed universal pulverizer, and sieve to obtain bacterial powder;

[0041] B, take bacterial powder, put into 3% salt treatment solution and soak for 8 hours, take out and dry, then soak in traditional Chinese medicine treatment solution for 15 hours;

[0042] C. Pour the soaked bacteria powder into the ethanol solution, and carry out microwave oscillation to obtain the extract of Antrodia camphorata.

[0043] In described step A, cross 800 mesh sieves.

[0044] The traditional Chinese medicine treatment liquid includes the following components by weight percentage:

[0045] Glycerin 1%

[0046] Pine Pollen 0.2%

[0047] water balance.

[0048] In the step C, the volume content of ethanol in the ethanol solution is 98%.

[...

Embodiment 3

[0051] An extraction method for improving the extraction effect of triterpenoids in Antrodia camphorata, comprising the following steps:

[0052] A, after cleaning and drying the appearance of the fruit body of Antrodia camphorata, pulverize by a high-speed universal pulverizer, and sieve to obtain bacterial powder;

[0053] B. Weigh the bacterial powder, put it into 5% salt treatment solution and soak for 4 hours, take it out and dry it, then soak it in the traditional Chinese medicine treatment solution for 24 hours;

[0054] C. Pour the soaked bacteria powder into the ethanol solution, and carry out microwave oscillation to obtain the extract of Antrodia camphorata.

[0055]In described step A, cross 325 mesh sieves.

[0056] The traditional Chinese medicine treatment liquid includes the following components by weight percentage:

[0057] Glycerin 0.5%

[0058] Pine Pollen 0.5%

[0059] water balance.

[0060] In the step C, the volume content of ethanol in the ethanol...

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Abstract

The invention discloses an extraction method for promoting an abstraction effect on a triterpene ingredient in antrodia camphorata. The extraction method comprises the following steps of firstly crushing the antrodia camphorata through a universal grinder, then soaking by using a traditional Chinese medicinal treatment solution, and finally abstracting by adopting ethanol to obtain an extract. Onthe basis of a conventional process, the step of soaking with the traditional Chinese medicinal treatment solution is added in the process of the extraction method. Glycerol and pollen pini are selected and mixed with water to obtain the traditional Chinese medicinal treatment solution; the traditional Chinese medicinal treatment solution is used after the soaking with sodium chloride; due to theconcentration difference of the sodium chloride, the sodium chloride in the antrodia camphorata can be continuously separated out until reaching concentration equilibrium; the infiltration of the glycerol and the pollen pini is more facilitated in a procedure; the protection to the triterpene ingredient in a soaking procedure is facilitated due to the addition of the glycerol; the structure of triterpene is prevented from being damaged; thus, more triterpene ingredients can be separated out, and the pollen pini has a synergetic effect with the triterpene in the antrodia camphorata.

Description

technical field [0001] The invention relates to the technical field of plant extraction, in particular to an extraction method for improving the extraction effect of triterpenoids in Antrodia camphorata. Background technique [0002] Antrodia camphorata, also known as Antrodia camphorata, belongs to the order Aphyllophyllaceae, Polyporaceae, Leptinosa, and perennial fungi. Its Latin name is Antrodia camphorata, and it is a new species published by the biochemical community in 1990. Its growth area is in the mountains and forests at an altitude of 450-2000 meters in Taiwan, China. It only grows on the inner wall of the rotten heartwood of the trunk of the camphor tree that is unique to Taiwan, China, and has a damp surface. Because it is not easy to collect, there are still social incidents of illegally harvesting Antrodia cinnamomea. heard. [0003] Antrodia cintrodia used to be a unique fungus in Taiwan, China, and only grew on the unique camphor tree in Taiwan, China. Wi...

Claims

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Application Information

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IPC IPC(8): A61K36/07A61P35/00A61P1/16
CPCA61K36/07A61K2236/10A61K2236/15A61K2236/333
Inventor 吴前禄
Owner 福州迈康医药科技有限公司
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