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Compound corn oligopeptide capsule and preparation method thereof

A technology of corn oligopeptide and corn oligopeptide powder, which is applied in capsule delivery, drug combination, pharmaceutical formula, etc., to achieve the effects of strong solubility, anti-aging, and easy absorption and utilization

Inactive Publication Date: 2018-08-17
覃静欣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are few reports on making corn oligopeptides into oral and external products

Method used

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  • Compound corn oligopeptide capsule and preparation method thereof
  • Compound corn oligopeptide capsule and preparation method thereof
  • Compound corn oligopeptide capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Preparation of Polygonatum Polygonatum Extract: Wash Polygonatum Polygonatum, dry, and pulverize to obtain Polygonatum Polygonatum Powder, mix Polygonatum Polygonatum Powder with ethanol solution with a volume fraction of 70% according to the ratio of solid to liquid at 1:10 (w / v) , keeping the temperature at 32°C, leaching for 5 hours under stirring conditions, then raising the temperature to 58°C for ultrasonic extraction for 15 minutes to obtain the extraction mixture, performing membrane filtration on the extraction mixture to obtain a mixed solution, and then concentrating the mixed solution under reduced pressure in vacuo to 11% of the original volume, then spray-dried to obtain Polygonatum odoratum extract;

[0031] Preparation of Houttuynia cordata extract: take Houttuynia cordata, wash, dry, and pulverize to obtain Houttuynia cordata powder, and mix Houttuynia cordata powder and ethanol solution with a volume fraction of 70% according to the ratio of material to...

Embodiment 2

[0037] Preparation of Polygonatum Polygonatum Extract: Wash Polygonatum Polygonatum, dry, and pulverize to obtain Polygonatum Polygonatum Powder, mix Polygonatum Polygonatum Powder with ethanol solution with a volume fraction of 70% according to the ratio of solid to liquid at 1:10 (w / v) , keeping the temperature at 30°C, leaching for 4 hours under stirring conditions, then raising the temperature to 55°C for ultrasonic extraction for 20 minutes to obtain the extraction mixture, performing membrane filtration on the extraction mixture to obtain a mixed solution, and then concentrating the mixed solution under reduced pressure in vacuo to 10% of the original volume, then spray-dried to obtain Polygonatum odoratum extract;

[0038] Preparation of Houttuynia cordata extract: take Houttuynia cordata, wash, dry, and pulverize to obtain Houttuynia cordata powder, and mix Houttuynia cordata powder and ethanol solution with a volume fraction of 70% according to the ratio of material to...

Embodiment 3

[0044] Preparation of Polygonatum Polygonatum Extract: Wash Polygonatum Polygonatum, dry, and pulverize to obtain Polygonatum Polygonatum Powder, mix Polygonatum Polygonatum Powder with ethanol solution with a volume fraction of 70% according to the ratio of solid to liquid at 1:10 (w / v) , keeping the temperature at 40°C, leaching for 4.2h under stirring conditions, then raising the temperature to 52°C for ultrasonic extraction for 16min to obtain the extraction mixture, performing membrane filtration on the extraction mixture to obtain a mixed solution, and then concentrating the mixed solution under reduced pressure in vacuo to 15% of the original volume, and then spray-dried to obtain Polygonatum odoratum extract;

[0045] Preparation of Houttuynia cordata extract: take Houttuynia cordata, wash, dry, and pulverize to obtain Houttuynia cordata powder, and mix Houttuynia cordata powder and ethanol solution with a volume fraction of 70% according to the ratio of material to liq...

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Abstract

The invention belongs to the technical field of oligopeptide powder processing, in particular to a compound corn oligopeptide capsule and a preparation method thereof. The compound corn oligopeptide capsule is prepared from the following raw material compositions in parts by weight: 30 to 40 parts of corn oligopeptide powder, 15 to 20 parts of sweet orange powder, 15 to 18 parts of xylitol, 12 to16 parts of tea polyphenol, 13 to 15 parts of theanine, 12 to 15 parts of chitosan oligosaccharide, 3 to 6 parts of vitamin E, 12 to 16 parts of citrus oil, 10 to 12 parts of sucrose ester, 8 to 12 parts of polygonatum odoratum extract, 6 to 8 parts of heartleaf houttuynia herb extract, 6 to 8 parts of oxalis corniculata extract, 6 to 8 parts of rubia cordifolia extract, and an appropriate amountof pure water. The preparation method comprises the following steps: preparing the polygonatum odoratum extract, the heartleaf houttuynia herb extract, the oxalis corniculata extract, and the rubia cordifolia extract from the raw materials respectively, and then preparing the raw materials into a microemulsion, and finally preparing the microemulsion into a capsule. The composite corn oligopeptidecapsule prepared by the method provided by the invention has the advantages of oral administration or external use, is good in effect, and is beneficial to human health.

Description

technical field [0001] The invention belongs to the technical field of oligopeptide powder processing, in particular to a compound corn oligopeptide capsule and a preparation method thereof. Background technique [0002] Oligopeptides, also known as oligopeptides, generally consist of 2 to 6 amino acids. Studies have shown that oligopeptides can be directly absorbed by the small intestine. Compared with proteins and amino acids, oligopeptides are easier to absorb in animals, and oligopeptides have unique physiological functions and physical and chemical properties, which are not available in original proteins or constituent amino acids. At present, people's research on oligopeptides is mainly in raw materials such as soybeans, fish skins, and animal bones. According to the source of raw materials, oligopeptides can be divided into animal-derived oligopeptides, plant-derived oligopeptides, and microbial-derived oligopeptides. The prepared oligopeptides can be used in the fi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A61K8/11A61K8/34A61K8/49A61K8/64A61K8/67A61K8/73A61K8/9789A61K8/9794A61K9/48A61P1/16A61P9/12A61P37/04A61P39/00A61Q19/02A61Q19/08A61K31/198A61K31/353A61K31/355A61K31/722A61K36/185A61K36/74A61K36/752A61K36/78A61K36/8969
CPCA61K38/011A61K8/11A61K8/345A61K8/498A61K8/645A61K8/678A61K8/736A61K8/9789A61K8/9794A61K9/4866A61K31/198A61K31/353A61K31/355A61K31/722A61K36/185A61K36/74A61K36/752A61K36/78A61K36/8969A61K2236/333A61K2236/51A61P1/16A61P9/12A61P37/04A61P39/00A61Q19/02A61Q19/08A61K2300/00
Inventor 覃静欣
Owner 覃静欣
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