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A Method for Realizing Two-Dimensional Phase-Sensitive J-Decomposition Spectroscopy of One-Voxel Localization

A technology of localized spectrum and spectral method, which is applied in the field of single-pixel localized two-dimensional phase-sensitive J-decomposition spectroscopy, which can solve the problem of reducing signal resolution and achieve high-resolution effects

Inactive Publication Date: 2019-10-22
XIAMEN UNIV
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Problems solved by technology

However, due to the influence of phase modulation on the JPRESS spectrogram, the spectrogram has to be displayed in absolute value mode, which reduces the resolution of the signal

Method used

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  • A Method for Realizing Two-Dimensional Phase-Sensitive J-Decomposition Spectroscopy of One-Voxel Localization
  • A Method for Realizing Two-Dimensional Phase-Sensitive J-Decomposition Spectroscopy of One-Voxel Localization
  • A Method for Realizing Two-Dimensional Phase-Sensitive J-Decomposition Spectroscopy of One-Voxel Localization

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Embodiment Construction

[0030] Below in conjunction with accompanying drawing and implementation example, the present invention will be further described:

[0031] A method for realizing single voxel localized two-dimensional phase-sensitive J-decomposition spectroscopy, comprising the following steps:

[0032] 1) Collect the MRI image of the sample, and determine the single-pixel localization area;

[0033] 2) collecting a one-dimensional localization spectrum of the single-pixel localization region;

[0034] 3) Determine the signal spectrum width of the one-dimensional localized spectrogram;

[0035] 4) measure the pulse width time of the 90 ° hard pulse of the sample and the power corresponding to the pulse width;

[0036] 5) Use the signal spectral width center of the one-dimensional localized spectrogram as the excitation center frequency of the small-angle flip sweep pulse, determine the pulse width and sweep range of the sweep pulse, and ensure that the sweep range is 2 to 5 times the signal...

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Abstract

The invention provides a method for realizing a single-voxel localized two-dimensional phase-sensitive J-decomposition spectrum. On the basis of a JPRESS sequence, a new sequence formed by a PYSCHE decoupling module formed by one pair of small-angle inverted sweep pulses and corresponding weak gradient fields and phased gradient fields is inserted before two 180-degree localized pulses, wherein the sequence is formed by N sequences formed at two sides of the 180-degree localized pulses before the PYSCHE decoupling module and P sequences formed at the two sides of the 180-degree localized pulses after the PYSCHE decoupling module during indirect dimensional evolution time; and the two-dimensional spectrum obtained by an N sequence experiment is overturned symmetrically along the indirect dimension F1=10 Hz and then the overturned two-dimensional spectrum is overlapped with a two-dimensional spectrum obtained by a P sequence experiment to obtain single-voxel localized two-dimensional phase-sensitive J-decomposition spectrum.

Description

technical field [0001] The invention relates to obtaining a two-dimensional localized J-decomposition spectrum on a nuclear magnetic resonance imaging instrument, in particular to a single-pixel localized two-dimensional phase-sensitive J-decomposition spectrum method that can be obtained by sampling on a nuclear magnetic resonance imaging instrument. Background technique [0002] Magnetic resonance localization (MRS) was developed in combination with nuclear magnetic resonance imaging (MRI) and nuclear magnetic resonance (NMR). Chemical composition and structure technology. Because MRS technology can realize non-invasive quantitative detection of selected tissues, it is an important bridge linking biochemical changes and disease pathology. At present, MRS technology has been used as a supplementary research tool of MRI technology, and has been widely used in clinical and medical research fields. Among them, point-resolved spectroscopy (Bottomley PA. Spatial Localization i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01R33/46A61B5/055
Inventor 林雁勤田丹陈忠
Owner XIAMEN UNIV
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