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Local anesthetic for tooth extraction as well as preparation method and application of local anesthetic

A local anesthetic, stirring reaction technology, applied in the direction of anesthetics, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve the problems of patient anxiety, allergic reactions, urticaria, etc., achieve high safety, easy industrial production, Simple preparation process

Inactive Publication Date: 2018-10-23
吕芳芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many problems with the existing local anesthetics: after injection of anesthetics, many patients experience uneasiness, paresthesia, anxiety, tinnitus, and perioral numbness; some patients have allergic reactions, urticaria, throat edema, and bronchospasm , hypotension, and angioedema
Therefore, although the curative effect of existing anesthetics is undeniable, its safety is worth pondering

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A local anesthetic for tooth extraction, comprising the following raw materials in parts by weight: 15 parts of aloe vera, 6 parts of Agaricus blazei, 5 parts of calamine, 10 parts of eucalyptus extract, 10 parts of cactus juice , 13 onions.

[0025] A preparation method of a local anesthetic for tooth extraction, comprising the following steps: (1) after dicing Agaricus blazei, adding 3 times the mass of water, and performing distillation; condensing the distilled gas containing the nutrients of Agaricus blazei to obtain Agaricus blazei Distillate, for subsequent use; (2) after onion, water and yeast are evenly mixed at a ratio of 10:100:1, sterilized after being fermented at room temperature for 10 days, and then centrifuged to take the supernatant to obtain an onion extract; (3) Aloe verain and onion extract were mixed, and stirred for 2 hours at 66°C; (4) Eucalyptus extract, cactus juice and Agaricus distillate were mixed, and stirred at 80°C for 20 minutes; (5) Gr...

Embodiment 2

[0027] A local anesthetic for tooth extraction, comprising the following raw materials in parts by weight: 22 parts of aloe vera, 12 parts of Agaricus blazei, 11 parts of calamine, 18 parts of eucalyptus extract, 20 parts of cactus juice , 28 onions.

[0028] A preparation method of a local anesthetic for tooth extraction, comprising the following steps: (1) after the Agaricus blazei is cut into pieces, adding 5 times the mass of water to carry out distillation; condensing the distilled gas containing the nutrient components of Agaricus blazei to obtain Agaricus blazei Distillate, for subsequent use; (2) after onion, water and yeast are mixed uniformly according to 20:200:1, placed at room temperature for 20 days of fermentation, sterilized, and then centrifuged to get supernatant to obtain onion extract; (3) Aloe verain and onion extract were mixed, and stirred at 80°C for 3 hours; (4) Eucalyptus extract, cactus juice and Agaricus distillate were mixed, and stirred at 90°C fo...

Embodiment 3

[0030] A local anesthetic for tooth extraction, comprising the following raw materials in parts by weight: 20 parts of aloe vera, 9 parts of Agaricus blazei, 8 parts of calamine, 15 parts of eucalyptus extract, 15 parts of cactus juice , 18 onions.

[0031] A preparation method of a local anesthetic for tooth extraction, comprising the following steps: (1) after the Agaricus blazei is cut into pieces, adding 4 times the mass of water for distillation; condensing the distilled gas containing the nutrient components of Agaricus blazei to obtain Agaricus blazei Distillate, ready for use. (2) After uniformly mixing onion, water and yeast at a ratio of 12:160:1, fermenting at room temperature for 15 days, sterilizing, and then centrifuging the supernatant to obtain an onion extract. (3) Aloe verain and onion extract were mixed, and the mixture was stirred and reacted at 75° C. for 2.3 hours. (4) The eucalyptus extract, the cactus juice and the Agaricus blazei distillate were mixe...

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PUM

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Abstract

The invention discloses a local anesthetic for tooth extraction as well as a preparation method and application of the local anesthetic. The local anesthetic for tooth extraction is prepared from thefollowing raw materials in parts by weight: 15-22 parts of aloesin, 6-12 parts of agaricus blazei murill, 5-11 parts of calamine, 10-18 parts of eucalyptus extract, 10-20 parts of cactus juice and 13-28 parts of onion. The local anesthetic provided by the invention is prepared from the aloesin, the agaricus blazei murill, the calamine, the eucalyptus extract, the cactus juice and the onion, and the raw materials are easy to obtain and environmentally friendly; clinical tests prove that the local anesthetic is free from toxic and side effects and does not cause complications, thus being high insafety; the local anesthetic can be used in an operation of tooth extraction, and has a response rate of 99%; the preparation method is simple in process and easy in realization of industrial production, thus being worth of popularization and application.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a local anesthetic for tooth extraction and a preparation method and application thereof. Background technique [0002] Anesthesia refers to the temporary and reversible loss of consciousness and pain sensation in the body or parts of the body by drug or non-drug methods, and is mostly used for surgery or the treatment of certain diseases. In tooth extraction surgery, local anesthesia is administered with western medicine injection. However, there are many problems with the existing local anesthetics: after the injection of the anesthetic, many patients experience anxiety, paresthesia, anxiety, tinnitus and perioral numbness; some patients have allergic reactions, such as urticaria, throat edema, and bronchospasm. , hypotension and angioedema. Therefore, although the efficacy of existing anesthetics is undeniable, its safety is worth pondering. The presen...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P23/02A61K33/30A61K31/352
CPCA61K31/352A61K33/30A61K36/07A61K36/33A61K36/61A61K36/8962A61K2236/19A61K2236/331A61P23/02A61K2300/00
Inventor 吕芳芳
Owner 吕芳芳
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